Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp8 | Adrenal | ECE2016

Adequate salt intake attenuates mineralocorticoid receptor antagonist-induced hyperkalemia in patients with primary aldosteronism

Fountoulakis Stelios , Papanastasiou Labrini , Piaditis George

Introduction: Mild hyperkalemia is a common side-effect of mineralocorticoid receptor antagonists (MRA), which can be precipitated by minimizing dietary salt intake. Restoration of salt intake can overcome diminished kaliuresis and restore potassium levels. Aim of this study was the evaluation of the effect of adequate salt consumption on plasma potassium levels in relation to the mean, maximum and minimum blood pressure (BP) in MRA-treated sodium-depleted hyperkalemic patient...

ea0032p470 | Diabetes | ECE2013

Monitoring and control of blood glucose levels in patients with inefficiently controlled insulin-treated diabetes mellitus through the utilization of an on-line telemonitoring system

Fountoulakis Stelios , Papanastasiou Labrini , Marakaki Chrisanthi , Anastasakou Marina , Piaditis George

Introduction: Our goal was to monitor and control the blood glucose levels in inefficiently controlled insulin-treated patients with diabetes mellitus (DM). The target was to achieve an early detection of DM deregulation, to maintain accepted HbA1c levels through active intervention and to minimize the outpatient department visits.Description of methods/design: Twenty-six insulin-treated type 1 and 2 DM patients were enrolled (mean age 61.42±14.5 ye...

ea0014p313 | (1) | ECE2007

Fas and FasL expression on peripheral lymphocytes in patients with autoimmune thyroid disease

Fountoulakis Stelios , Vartholomatis George , Philippou George , Tsatsoulis Agathocles

Objective: The Fas/Fas ligand (FasL) apoptotic pathway is activated in patients with autoimmune thyroid disease (AITD). It is believed that Fas and FasL expression in intrathyroidal T lymphocytes and thyrocytes is regulated in a manner resulting in thyroid cell apoptosis in Hashimoto’s thyroiditis (HT) or lymphocyte apoptosis in Graves’ disease (GD). The hypothesis that Fas and FasL may be differentially expressed on peripheral lymphocytes in patients with HT and GD ...

ea0035p475 | Diabetes therapy | ECE2014

Improvement of HbA1c is blunted following discontinuation of an on-line telemonitoring system, in patients with inefficiently controlled insulin-treated diabetes mellitus

Fountoulakis Stelios , Papanastasiou Labrini , Malliopoulos Dimosthenis , Marakaki Chrisanthi , Markou Athina , Kounadi Theodora , Piaditis George

Aim: Primary goal was to determine whether the improvement of HbA1c, observed in inefficiently insulin-treated diabetes mellitus (DM) patients on a telemonitoring system, had a lasting effect following its discontinuation.Methods: Forty-seven DM patients (mean age 56.15±15.86 years, mean BMI 29.44±6.69 kg/m2, mean HbA1c 9.9±2.62%) and 25 insulin-treated matched controls (mean age 56.16±20.11 years, mean BMI 27.6±5.18 k...

ea0041gp23 | Adrenal (2) | ECE2016

Deterioration of indices of insulin resistance in patients with non-functioning and cortisol secreting adrenal incidentalomas during a long term follow-up

Papanastasiou Labrini , Alexandraki Krystallenia , Fountoulakis Stelios , Kounadi Theodora , Markou Athina , Tsiavos Vaios , Androulakis Ioannis , Samara Christianna , Piaditis George , Kaltsas Gregory

Introduction: Adrenal incidentalomas (AI) with or without concomitant autonomous cortisol secretion can be associated with several metabolic alterations that may lead to increased cardiovascular risk. However, data regarding insulin resistance (IR) during long term follow-up of AI are scarce. The aim was to prospectively investigate the presence and evolution of IR in patients with AI between 2003 and 2014.Methods: Seventy three patients with AI for at l...

ea0035p979 | Thyroid (non-cancer) | ECE2014

Ultrasound-guided thyroid fine needle aspiration with rapid on-site evaluation of adequacy: data from the clinic of endocrinology of a Greek tertiary general hospital in 2013

Fountoulakis Stelios , Papanastasiou Labrini , Koutmos Spiros , Charalambous Pinelopi , Stratigaki Aimilia , Panagouli Pelagia , Lazari Paraskevi , Asimis Eleptherios , Vlahou Melpomeni , Piaditis George

Introduction: Ultrasound-guided fine needle aspiration biopsy (US-FNAB) enables selective sampling of thyroid follicular cells while minimizing potential complications. Inadequate specimen sampling can lead to FNAB repeat. Our aim was to evaluate the morphological and cytological characteristics of thyroid nodules with US and rapid on-site evaluation of adequacy (ROSE).Methods: Two independent endocrinologists evaluated nodule characteristics of 171 US-F...

ea0032p46 | Adrenal cortex | ECE2013

Autonomous aldosterone secretion as a significant cause of arterial hypertension: the effectiveness of targeted therapy

Papanastasiou Labrini , Pappa Theodora , Fountoulakis Stelios , Tsounas Panagiotis , Markou Athina , Tsiavos Vaios , Anastasakou Marina , Marakaki Chrisanthi , Malliopoulos Dimosthenis , Kounadi Theodora , Piaditis George

Introduction: The prevalence of autonomous aldosterone secretion (AAS) in hypertensive subjects varies due to the use of various suppression tests and cut-off values. Our aim was to evaluate the prevalence of AAS in hypertensive subjects and test the anti-hypertensive effect of targeted treatment of the renin angiotensin II aldosterone system (RAAS) in AAS subjects.Description of methods/design: We investigated 336 hypertensive subjects with and without ...