Searchable abstracts of presentations at key conferences in endocrinology

ea0056p589 | Obesity | ECE2018

Association between Leptin gene polymorphisms and plasma leptin level in three consanguineous families with obesity

Fourati Mouna , Hadjkacem Faten , Ghorbel Dorra , Mrabet Houcem Elomma , Sessi Salwa , Fakhfakh Faiza , Abid Mohamed

Leptin (LEP) gene is one of the most promising candidate genes for obesity. The aim of this study was to investigate the impact of LEP polymorphisms on obesity, anthropometric and biochemical parameters in a sample of three Tunisian consanguineous families with obesity. Seven single nucleotide polymorphisms (SNPs) in 5′ region of LEP gene were genotyped in three consanguineous families including 33 individuals. The previously reported LEP</...