Searchable abstracts of presentations at key conferences in endocrinology

ea0022p475 | Female reproduction | ECE2010

Endothelial structure and function in young women with polycystic ovary syndrome: a 5 years follow-up study

Orio Francesco , Giallauria Francesco , Grieco Alessandra , Caggiano Chiara , Lombardi Gaetano , Caggiano Domenico , Palomba Stefano , Colao Annamaria

To date, studies focusing on long-term cardiovascular risk (CVR) of polycystic ovary syndrome (PCOS) women are not available, as well as longitudinal data regarding the endothelial structure and function.The aim of this observational study was to examine both endothelial structure and function in young women with PCOS at 5-year follow-up.Thirty PCOS women (age 22.2±2.5 years, mean±S.D.; BMI 22.4±2.1, k...

ea0014p633 | (1) | ECE2007

Three months exercise training improves cardiopulmonary functional capacity in polycystic ovary syndrome

Orio Francesco , Giallauria Francesco , Palomba Stefano , Cascella Teresa , Vuolo Laura , Tafuri Domenico , Manguso Francesco , Lombardi Gaetano , Colao Annamaria , Vigorito Carlo

Introduction and Aim: Polycystic Ovary Syndrome (PCOS) is an endocrine disease closely related to several risk factors for cardiovascular disease. Previous study demonstrated an impaired cardiopulmonary functional capacity in PCOS women. The present study was performed to evaluate the effects of 3-months exercise training (ET) programme on cardiopulmonary functional capacity in young women with PCOS.Patients and Methods: The study was conducted according...

ea0022p476 | Female reproduction | ECE2010

Structured exercise training plus hypocaloric diet improves ovarian sensitivity to clomiphene citrate in polycystic ovary syndrome (PCOS) patients

Palomba Stefano , Giallauria Francesco , Falbo Angela , Russo Tiziana , Grieco Alessandra , Colao Annamaria , Lombardi Gaetano , Orio Francesco

Clomiphene citrate (CC) is the first-line therapy for inducing ovulation in infertile women with polycystic ovary syndrome (PCOS), but about 20% of them results un-responsive. Lifestyle modification programs are effective in restoring ovarian function and improving reproductive outcomes in PCOS patients.The aim of the present randomized controlled trial was to test the hypothesis that a very short-term intervention consisting in structured exercise train...

ea0014oc11.6 | Reproductive endocrinology II | ECE2007

Visceral fat amount as predictor for subclinical cardiovascular disease in women with polycystic ovary syndrome

Cascella Teresa , Palomba Stefano , De Sio Ilario , Manguso Francesco , Vuolo Laura , Giallauria Francesco , Grieco Alessandra , Lombardi Gaetano , Colao Annamaria , Tafuri Domenico , Orio Francesco

Introduction and aim: Polycystic Ovary Syndrome (PCOS) is a common disorder associated with a wide range of endocrine and metabolic abnormalities. Obesity is present in about 45–50% of PCOS women. Increased cardiovascular risk factors and evidence of subclinical cardiovascular disease (CVD) have been reported in PCOS. The aim of the present study was to evaluate whether visceral fat amount may be considered as predictor for early CVD in PCOS women.P...

ea0014p634 | (1) | ECE2007

Abnormal heart rate recovery after maximal cardiopulmonary exercise stress testing in polycystic ovary syndrome

Giallauria Francesco , Palomba Stefano , Cascella Teresa , Vitelli Alessandra , Maresca Luigi , Grieco Alessandra , Tafuri Domenico , Colao Annamaria , Lombardi Gaetano , Vigorito Carlo , Orio Francesco

Introduction and aim: Polycystic ovary syndrome (PCOS) is associated with an adverse metabolic and cardiovascular risk (CVR) profile, including: diabetes, insulin resistance, dyslipidemia and hypertension. Heart rate recovery (HRR) is a measure of autonomic dysfunction and an abnormal HRR is also associated with increased mortality. To date, no evaluation of autonomic function in young PCOS women has been performed, therefore the aim of the present study was to evaluate the HR...