Endocrine Abstracts

Introduction: Two identically designed randomized, placebo-controlled double-blind studies (one conducted in North America and the other one in Europe and Australia) showed that an oral contraceptive containing estradiol valerate (E2V)/dienogest (DNG) in an estrogen step-down, progestogen step-up 28-day regimen was effective in women with heavy and/or prolonged menstrual bleeding without organic pathology. Both studies applied a strict definition of treatment succes...

Background: There is uncertainty regarding the selection of obese patients for metabolic procedures, how to define a successful outcome and pre-operative predictors of success. Our aim was to explore the influence of obesity on preoperative quality of life in patients awaiting bariatric surgery.Methods: Pre-operative data were accrued for morbidly obese patients (n=70) at the University Hospitals Coventry and Warwickshire (UHCW) during the last ...

Background: Pre-operative predictive measures of post-metabolic surgery success would facilitate a more refined evidence-based selection of patients. This study aimed at identifying those clinical and psycho-social predictors of success (defined as weight-loss) following metabolic surgery.Methods: Pre-operative data including IWQOL-Lite questionnaire (a validated self-reported 31-item measure of physical function, self-esteem, sexual life, public distres...