ea0011p472 | Endocrine tumours and neoplasia | ECE2006
van der Klaauw AA
, Pereira AM
, van Thiel SW
, Smit JWA
, Corssmit EPM
, Biermasz NR
, Frohlich M
, Iranmanesh A
, Veldhuis JD
, Roelfsema F
, Romijn JA
Growth hormone deficiency frequently occurs as consequence of radiation therapy in pituitary disorders. However, it not known whether radiation therapy in acromegaly results in comparable diminution of GH secretion. We therefore hypothesized that stimulated and spontaneous GH release is ultimately indistinguishable in irradiated acromegalic patients and irradiated patients with other pituitary disorders. For this study 10 acromegalic patients and 10 patients with other pituita...