ea0026p389 | Thyroid (non cancer) | ECE2011
, Pawlak-Adamska E
, Bolanowski M
, Frydecka I
Introduction: Both genetic and environmental factors contribute to clinical manifestation of Graves disease including the response to medical therapy. CTLA-4 gene is an important inhibitor of T-cell activation and its polymorphisms may influence the course of the disease.Goal: We investigated the association between CTLA−4 gene polymorphisms: c.49A>G, g.319C>T, g.*642AT(8_33), CT60, and Jo31 and the response to ph...