Searchable abstracts of presentations at key conferences in endocrinology

ea0035p933 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

An unusual cause of hypopituitarism

Sivakumaran D , Mlawa G , Bano G

A 64-year-old Sri Lankan female was admitted with a 1 week history of vomiting and poor oral intake. She had an episode of pneumonia 4 months previously and reported headaches, weight loss and dizziness since then.On admission, her blood tests showed marked hyponatraemia with a sodium of 118 mmol/l and low serum osmolality of 243 mOsm/kg. A short synacthen test confirmed adrenal insufficiency and thyroid function tests showed secondary hypothyroidism des...

ea0065p334 | Neuroendocrinology | SFEBES2019

Co-secreting TSH and growth hormone pituitary adenoma

Eid Hatem , Andrabi B , Ismail R , Nizar H , Maltese G , Bano G

The co-existence of thyrotropin (TSH) and growth hormone (GH) secreting pituitary adenoma is exceedingly rare. Less than 15 cases having been reported.Case report: A 75 years’ old man presented with new-onset atrial fibrillation. He had high FT4 with normal TSH. His ultrasound scan of the neck showed a solitary nodule. He had ablation twice and was started on bisoprolol and anticoagulant. He had an MRI scan for headaches and this showed a pituitary ...

ea0062wc5 | Workshop C: Disorders of the thyroid gland | EU2019

Interpretation of abnormal thyroid function tests

Eid Hatem , Bano G

Background: In the majority of cases, the results of TFTs are straightforward. In significant subgroup of patients, the interpretation of TFTs is more challenging, either because. The results appear discordant with the clinical picture (e.g. normal TSH in a patient with suspected thyrotoxicosis), Or measurements appear to contradict each other (e.g. raised TH concentrations, but with non-suppressed TSH).Case presentation: 29 year old Caucasian female com...

ea0010p7 | Clinical case reports/Governance | SFE2005

A rare cause of hypokalaemia

Brackenridge A , Bano G , Nussey S

A 26 year old lady presented to her general practitioner complaining of fatigue. Investigations showed serum potassium of 2.5 mmol/l, (reference range 3.3–4.7 mmol/l). This was repeated on two more occasions and was 2.6 and 2.8 mmol/l. An ECG showed no features of hypokalaemia. She was seen in Endocrine clinic with serum potassium of 2.5 mmol/l. There was no history of an eating disorder, laxative or diuretic abuse. Her father had type 2 diabetes. Her height was 1.56 m a...

ea0007p73 | Diabetes, metabolism and cardiovascular | BES2004

A comparison of the impact of exercise in Asian and Caucasian women with Polycystic Ovary Syndrome

Banerjee A , Bano G , Kaushal R

Background: Hyperinsulinaemia and insulin resistance is observed in both lean and obese women with Polycystic Ovary Syndrome (PCOS). This condition affects 52% of Asian Indian compared to 22% of Caucasian women. Lifestyle changes, particularly diet and exercise can significantly impact the future prevention of type 2 diabetes, dyslipidaemia and hypertension in these patients.Objectives: We hypothesised that regular intensive exercise would be effective i...

ea0007p238 | Thyroid | BES2004

Multiple thyroid tumours

Qureshi A , Bano G , Nussey S

The majority of clinically palpable masses affecting the thyroid are benign. Malignant thyroid tumours are the commonest endocrine malignancies yet are rare. Most are of a single distinct cellular type, though mixed cellularity tumours also occur, the commonest of which is papillary and follicular. We describe 2 cases with more than one differentiated tumour in each thyroid gland.CASE 1A 44y builder with a family history of medulla...

ea0006p6 | Clinical case reports | SFE2003

Gestational DI and oligohydramnios

Qureshi A , Bano G , Nussey S

A 27y old woman presented with a 2yr history of secondary amenorrhoea and mild hyperprolactinaemia. CT scan demonstrated an enlarged pituitary gland abutting the optic chiasm. Goldman perimetery was normal and trans-sphenoidal hypophysectomy undertaken. Post-operatively she suffered temporary diabetes insipidus responding well to desmopressin. At endocrine assessment, she was growth hormone deficient, had partial diabetes insipidus and a sub-optimal cortisol response. Desmopre...

ea0005p188 | Neuroendocrinology and Behaviour | BES2003

Treating hyperprolactinaemia: Where to draw the line?

Qureshi A , Bano G , Nussey S

BackgroundA fear of rising serum prolactin concentrations (PRO) and pituitary tumour enlargement undoubtedly result in over-treatment of some patients with pathological hyperprolactinaemia. In recent years, our unit has adopted pragmatic criteria for discontinuing dopamine agonist (DA) therapy in selected patients. These include: small (or no) abnormality of pituitary imaging; presentation PRO<2,000milliunits per litre; small DA dose; stable PRO; women with a history of...

ea0019p51 | Clinical practice/governance and case reports | SFEBES2009

Intestinal neurofibromatosis and subclinical Cushing’s syndrome

Malik I , Panahloo A , Chong WH , Bano G

A 55-year-old gentleman was referred to surgeons for screening colonoscopy in view of family history of bowel cancer. His mother, maternal aunt and two cousins had history of bowel cancer. When seen by the surgeons, he gave 4-month history of intermittent abdominal bloating and rectal bleeding. His past medical history included a recent diagnosis of hypertension, a chronic history of facial neuralgia and history of excision of numerous facial skin tags. He was on amlodipine 5 ...

ea0015p164 | Endocrine tumours and neoplasia | SFEBES2008

Unsteady amenorrhoea

Pusalkar Pawan , Nussey S , Bano G

A 26-year-old Caucasian female presented with nausea, intermittent abdominal pain and amenorrhoea of 3 months duration. She was known to have Von Hippel–Lindau disease (Exon 3A/T 742 mutation) and had undergone surgery for cerebellar haemangioblastoma. She also had presumed dermoid cyst in right ovary which had been monitored by ultrasound. Ultrasound revealed an increase in size and vascularity of right ovarian cyst. MRI scan revealed it to be a 6.3 cm lobulated mass in ...