ea0029oc1.5 | Pituitary Clinical I | ICEECE2012
Muller H.
, Gebhardt U.
, Warmuth-Metz M.
, Kortmann R.
, Faldum A.
, Pietsch T.
, Gabriele C.
, Sorensen N.
Hypothalamic obesity has major impact on prognosis and quality of life (QoL) in childhood craniopharyngioma (CP). The pathogenic relevance of initial hypothalamic involvement versus treatment-related hypothalamic lesions is a matter of controversy.One hundred and twenty patients were recruited prospectively during 2001 and 2007 and evaluated after 3 years of follow-up. Body mass index (BMI) and QoL at diagnosis and 36 mo after diagnosis were analyzed bas...