ea0022p530 | Male reproduction | ECE2010
Trabado Severine
, Maione Luigi
, Salenave Sylvie
, Baron Stephanie
, Galland Francoise
, Sinisi Antonio-Agostino
, Brailly-Tabard Sylvie
, Young Jacques
Context: Congenital hypogonadotropic hypogonadism (CHH), is a rare disorder associated with severe testosterone deficiency and with impaired bone mineral mass (BMM) acquisition and osteoporosis. Estradiol (E2) play a major role in bone development and maintain in BMM in humans.Objective: To evaluate in detail the degree of E2 deficiency in adult men with CHH.Design and patients: Using a sensitive E2...