ea0099p442 | Adrenal and Cardiovascular Endocrinology | ECE2024
Said Wogud Ben
, Lempesis Ioannis
, Garcia Silvia Fernandez
, Thangaratinam Shakila
, Arlt Wiebke
, Idkowiak Jan
Background: Androgen excess frequently manifests in pre-pubertal children as premature adrenarche (PA). PA is characterised by the development of pubic and axillary hair, adult-type body odour in girls <8yrs and in boys <9yrs. PA may be a forerunner condition of polycystic ovary syndrome (PCOS), a complex metabolic disorder characterised by androgen excess. It is well established that women with PCOS have high risk of insulin resistance and frequently develop type 2 di...