ea0063p989 | Diabetes, Obesity and Metabolism 3 | ECE2019
Inacio Isabel
, Azevedo Teresa
, Alves Marcia
, Dantas Rosa
, Balsa Ana Margarida
, Ferreira Sara
, Rosinha Patricia
, Gomes Fernanda
, Fonseca Catarina
, Garret Ana
, Jesus Andreia
, Guimaraes Joana
Introduction: The American Diabetes Association guideline states that the long-term use of metformin may be associated with biochemical vitamin B12 (B12) deficiency and periodic measurement should be considered, although isolated serum B12 measurement has low sensitivity and specificity. Homocysteine (Hcy) and methylmalonic acid (MMA) are more sensitive biomarkers, the latter being more specific.Objectives: To estimate B12 deficiency in type 2 diabetics ...