Endocrine Abstracts

Hashimoto’s thyroiditis is an autoimmnune condition most common in females but can be also found in children with a prevalence of 1.2%. When is associated with hypothyroidism, the growth delay is an important, but late symptom. We present the case of a 12-year-old boy presenting with small height for age (123 cm, <−3 S.D.), important weight gain and fatigue. He was the only child from parents of average height and had normal weight at birth (3300 ...

Introduction: High-resolution ultrasound (US) allows the location of large parathyroid adenomas. These tumours should be however differentiated from thyroid nodules. For the confirmation of the parathyroid adenoma, we propose US-guided fine-needle aspiration biopsy (FNAB) of suspected nodules, with additional parathyroid hormone (PTH) analysis in the washout of the aspirate (PTH-FNA).Case report: A 51-year old woman with recently installed menopause and ...

Published data regarding the role of FGF23 in primary hyperparathyroidism and its prognostic applicability are scarce and discordant.Aims: To assess FGF23 profile in patients with primary hyperparathyroidism undergoing surgery.Matherials and methods: Longitudinal study involving 48 patients aged 30–80 years with primary hyperparathyroidism caused by solitary parathyroid adenoma, submitted to parathyroidectomy. We evaluated FGF...

Background: Vitamin D deficiency is frequently associated with primary hyperparathyroidism, but the impact of this association on disease evolution and complications is ill defined. Aims: to assess the role of vitamin D status on the metabolic profile and spectrum of complications at patients with primary hyperparathyroidism.Materials and methods: Transversal study involving 42 patients with primary hyperparathyroidism submitted to parathyroidectomy. We ...

Background: D hypovitaminosis and primary hyperparathyroidism frequently coexist. Secondary hyperparathyroidism reactive to D hypovitaminosis is difficult to be differentiated from primary hyperparthyroidism.Aims: To differentiate patients with D hypovitaminosis and secondary hyperparathyroidism.Materials and methods: Prospective study involving 71 patients admitted in our department for 1 year with the initial diagnosis of primary...

Aim: Fibroblast growth factor-23 (FGF-23) has been proposed as a predictor of bone abnormalities in chronic kidney disease patients (CKD), with recent data showing that it may also predict bone mass in the general population. We aimed at investigating the relationship between FGF-23 and bone mass parameters in apparently healthy individuals, according to sex, menopausal and nutritional status.Materials and methods: Bone mass (bone mineral density-BMD, bo...