Searchable abstracts of presentations at key conferences in endocrinology

ea0063gp23 | Calcium and Bone 1 | ECE2019

Study of hsa-miR-30e miRNA as a biomarker in identifying multiple gland disease in sporadic primary hyperparathyroidism: Is it time for individualized molecular-based surgery?

Mizamtsidi Maria , Nastos Konstantinos , Palazzo Fausto , Constantinides Vasilis , Dina Roberto , Farenden Megan , Vassiliou Ioannis , Gazouli Maria

Introduction: Sporadic primary hyperparathyroidism (sporadic PHPT) is a common endocrine disorder, usually caused by a single parathyroid adenoma. However, up to 15% of patients present with multiple gland disease (MGD), which cannot be always diagnosed preoperatively, raising serious management problems. No predictive genetic screening tests are currently available to distinguishing adenomas from MGD in sporadic PHPT. MiRNAs are widely established as genetic molecules that ha...

ea0032p603 | Female reproduction | ECE2013

PON1-108 TT and PON1-192 RR genotypes are more frequently encountered in Greek PCOS than non-PCOS women, and are associated with hyperandrogenemia

Mastorakos George , Paltoglou George , Tavernarakis George , Christopoulos Panagiotis , Vlassi Margarita , Gazouli Maria , Deligeoroglou Efthimios , Creatsas George

Objective: To investigate the frequencies of three paraoxonase (PON)1 polymorphisms in Greek polycystic ovary syndrome (PCOS) and non-PCOS women, and their genotypes in association with hyperandrogenemia and insulin resistance.Design: Case–control genetic association study.Patients: PCOS cases (NIH criteria) and 112 controls.Main outcome measure: Genotyping of the c.−108C>T (PON1-108), the c.16...