Searchable abstracts of presentations at key conferences in endocrinology

ea0014p112 | (1) | ECE2007

Isolation of the Side population (SP) from murine adrenal glands renders cells with adrenocortical stem cell properties

Lichtenauer Urs , Shapiro Igor , Geiger Klaus , Pulichino Anne-Marie , Drouin Jaques , Beuschlein Felix

Radioactive and transgenic tracing experiments indicate that in the adult adrenal stem cells persist in the periphery of the cortex, which migrate centripetally and populate the inner cortical zones upon differentiation. However, investigation of these cells has been hampered by the lack of known marker genes. Vital Hoechst dye exclusion has been described as a method for isolating a side population (SP) from mouse bone marrow, which was enriched with stem cells. Utilizing thi...