Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep846 | Clinical case reports - Pituitary/Adrenal | ECE2017

Breast cancer and newly discovered non-secretor pituitary mass- as risk of metastases?

Valea Ana , Oprisor Iulia , Carsote Mara , Pop Dan Dumitru , Morar Andra , Ghervan Cristina , Georgescu Carmen Emanuela

Introduction: Even if breast cancer is rare cause of pituitary metastases, the diagnosis of a pituitary adenoma, shortly after surgery for breast cancer, raises suspicion of a possible secondary determinations.Material and method: This is a case report revealing the medical history and endocrine profile of a female with breast cancer and pituitary macroadenoma.Case data: A 64-year old non-smoking female (with menopause at age of 52...

ea0041ep49 | Adrenal cortex (to include Cushing's) | ECE2016

Cushing’ s disease, hasimoto’s thyroiditis and severe hyperandrogenemia

Valea Ana , Ciocan Irina , Carsote Mara , Morar Andra , Pop Dan Dumitru , Ghervan Cristina , Georgescu Carmen Emanuela

Introduction: Cushing’s disease (CD) is caused by high adrenocorticotropic hormone (ACTH), usually by a pituitary microadenoma.Material and method: This is a case report investigated in several Romanian centers by performing: morning plasma cortisol, circadian rhythm of plasma cortisol, plasma ACTH, dexamethasone (DXM) suppression tests.Case data: A 57-year female, known with hypertension and osteopenia, was ...

ea0041ep81 | Adrenal cortex (to include Cushing's) | ECE2016

Asynchronous bilateral adrenal masses: from surgery to endocrine follow-up

Valea Ana , Ciocan Irina , Pop Dan Dumitru , Carsote Mara , Muntean Iulia , Ghervan Cristina , Georgescu Carmen Emanuela

Introduction: Cushing’s syndrome (CS) is correlated with prolonged exposure to high levels of glucocorticoid hormones. Although the most common cause is exogenous adrenal tumors incidentally discovered (incidentaloma) may underline CS.Material and method: This is a case presentation of an adult patient. Specific tests for CS have been used: morning plasma cortisol and circadian rhythm, plasma ACTH, testosterone, dexamethasone (DXM) suppression test....

ea0041ep167 | Calcium and Vitamin D metabolism | ECE2016

Adult iatrogenic hypoparathyroidism therapy: between less and more

Terec Adina , Morar Andra , Carsote Mara , Pop Dan Dumitru , Georgescu Carmen Emanuela , Valea Ana

Introduction: The hypoparathyroidism (HypoPT) represents a rare condition characterized by low calcium (Ca) and parathyroid hormone (PTH) levels, frequently due to thyroid surgery by direct trauma of the parathyroid glands, devascularization, or their accidental removal. Postoperative hypoparathyroidism-related hypocalcemia may be permanent or transient.Case report: We report the case of a 64-year-old man presenting with severe symptoms of hypocalcemia (...

ea0056p98 | Clinical case reports - Pituitary/Adrenal | ECE2018

High Adrenocorticotropic Hormone before and after bilateral adrenal surgery

Valea Ana , Turturea Roxana , Botezan Oana , Carsote Mara , Botezan Bogdan Mircea , Georgescu Carmen Emanuela

Introduction: Paraneoplastic Cushing syndrome is a rare form of endogenous ACTH (adrenocorticotropic hormone) dependent hypercortisolism. In some cases no overt ACTH secretion tumor can be found, which is why steroidogenesis inhibitors, and bilateral adrenalectomy remain the main therapeutic options.Material and method: This is a case report investigated in several centers by performing biochemical, hormonal and imagery tests.Case ...

ea0056p327 | Clinical case reports - Thyroid/Others | ECE2018

Diabetes and bulimia – a dangerous combination

Cosma Daniel Tudor , Silaghi Cristina Alina , Silaghi Horatiu , Georgescu Carmen Emanuela , Veresiu Ioan Andrei

Introduction: Bulimia is an eating disorder characterized by constant preoccupation with food, irresistible cravings for food and binge eating episodes. The data regarding the incidence of bulimia in people with diabetes are contradictory. The glycemic variations subsequent to binging and vomiting leads to complications like retinopathy, kidney or liver failure, hypoglycemic comas and electrolyte imbalances.Case presentation: A 57-year-old female, diagno...

ea0056p328 | Clinical case reports - Thyroid/Others | ECE2018

Prolonged hyperglycemia in a type 1 diabetic futsal player after a single betamethasone injection for pain in the groin area

Cosma Daniel Tudor , Silaghi Cristina Alina , Silaghi Horatiu , Georgescu Carmen Emanuela , Veresiu Ioan Andrei

Introduction: Pain in the groin area is frequently encountered in football players, the cause being a sport hernia, muscle tears, avulsions, sacroiliac joint pathology, etc. Local corticosteroid injections (LCIs) are often used as one of the first-line treatments in the conservative management because of their ease of delivery, low cost and efficacy.Case presentation: A 32-year-old amateur futsal player (goalkeeper) diagnosed with type 1 diabetes at the ...

ea0073aep484 | Pituitary and Neuroendocrinology | ECE2021

Spontaneous remission of cushing’s disease – a case report

Curt Ana Maria , Georgescu Carmen Emanuela , Bintintan Adriana , Ioana Rada Popa Ilie

Adrenocorticotropic hormone (ACTH) adenomas causing Cushing’s disease (CD) have been recognized as an aggressive and invasive subtype of pituitary adenomas. Remission of CD without surgical or medical treatment is an extremely rare occurrence. Moreover, a clinically relevant peculiarity of these tumors, though rarely observed, is their ability to modify their clinical expression from a silent form to CD or vice versa, the latter even more unexpected. We describe the case ...

ea0063gp64 | Reproductive Axis | ECE2019

Untargeted lipidomics profiling by high-performance liquid chromatography/time-of-flight mass spectrometry in polycystic ovary syndrome: candidate biomarkers and association to disease traits

Georgescu Carmen Emanuela , Vonica Camelia , Ilie Ioana Rada , Moraru Corina , Pop Dana , Hazi Georgeta , Pinzariu Oana , Socaciu Carmen

Background: Metabolomics profiling of bio-fluids suggests altered signatures in patients with the polycystic ovary syndrome (PCOS).Subjects and methods: A high-performance liquid chromatography/time-of-flight mass spectrometry (HPLC/TOF-MS)-based metabolomics approach was developed to characterize the untargeted lipidomics signature associated with PCOS status in a discovery cohort of 30 plasma samples (15 PCOS, 15 controls, age-matched), followed in a s...

ea0063ep7 | Adrenal and Neuroendocrine Tumours | ECE2019

Adrenal carcinoma presenting as suicidal depression

Petrescu Denisa , Georgescu Carmen Emanuela , Crisan Catalina , Silaghi Horatiu , Suciu-Petrescu Malina , Lungu Ionela , Silaghi Cristina Alina

Depression can be an early manifestation of Cushing Syndrome (CS) and found to correlate with the severity of the clinical presentation. Rates for major depression vary from 12% to 50–70%. A 37-year-old male was admitted for sad mood, affective lability, suicidal ideation without a plan and micromanian incurability ideation. The medical history of the patient revealed an old anterior-lateral myocardial infarction last year, with percutaneous coronary intervention on diago...