Searchable abstracts of presentations at key conferences in endocrinology

ea0065p287 | Neuroendocrinology | SFEBES2019

Cannulated prolactin as a diagnostic tool for true hyperprolactinaemia

Machenahalli C Pratibha , Giovos Georgios , Randeva Harpal , Smith Megan

Background: Hyperprolactinaemia is the common endocrine disorders. More commonly diagnosed in women due to menstrual irregularity, infertility and galactorrhoea. Hyperprolactinaemia can be due to many physiological stimuli such as stress, sleep, exercise, medications, primary hypothyroidism, renal failure, chest wall lesion. Stress of venepuncture can contribute to hyperprolactinaemia as well.Patient and methods: We conducted a retrospective analysis of ...

ea0086p108 | Neuroendocrinology and Pituitary | SFEBES2022

Dopamine agonist intolerance in prolactinoma- A management challenge to endocrinologist

Wellala Vindya , Machenahalli Pratibha , Kumarathunga Dineesha , Georgios Giovos , Puja Thadani

Introduction: Typically, patients with a microprolactinoma will have serum prolactin level between 2,000-4,000mIU/l. The primary goal of treatment is to normalise prolactin level and thereby improve symptoms associated with a raised prolactin. Dopamine (D2) agonists are the main stay of treatment with some patients unable to tolerate dopamine agonists rather than being resistant to the medication.Case report: A 26-year-old lady with a history of anxiety ...

ea0077p97 | Neuroendocrinology and Pituitary | SFEBES2021

Management of Complicated Pit-1 staining Non-functioning Pituitary macroadenoma in Pregnancy

Machenahalli Pratibha , Thandani Puja , Shad Amjad , Sherlala Khalid , Giovos Georgios , Dhingra Vandana , Randeva Harpal

Background: Incidence of non-functioning pituitary macroadenoma (NFPMA) is very rare in pregnancy. We describe a case of complicated non-functioning pituitary macroadenoma presented during pregnancy. 26 year old female at 21 weeks gestation presented to emergency services with worsening headaches, nausea and vomiting for 2-3 months. This was associated with transient double vision and confusion since 2 days. She was admitted to emergency department 3 weeks ago with vomiting an...

ea0075p07 | Pituitary and neuroendocrinology | EYES2021

Pregnancy and diabetes insipidus – A management conundrum

Thadani Puja , Khan Uzma , Giovos Georgios , Smith Megan , Dhingra Vandana , Shad Amjad , Randeva Harpal , Machenahalli Pratibha

Background: Diabetes Insipidus (DI) is uncommon during pregnancy. It may predate pregnancy, be unmasked by pregnancy or arise de novo during pregnancy secondary to other pathology. We present a case of DI in pregnancy to highlight challenges in management.Case Report: A 27-year-old lady at 21 weeksÂ’ gestation, presented to A&E with worsening headache and confusion for three to five months. She was hemodynamically stable, had bitemporal hemianopi...

ea0077p99 | Neuroendocrinology and Pituitary | SFEBES2021

Retrospective audit of clinical, biochemical and radiological features of Pituitary apoplexy

Machenahalli Pratibha , Shad Amjad , Shrelala Khalid , Thandani Puja , Giovos Georgios , Khan Uzma , Page Tristan , Haris Faiza , Smith Megan , Randeva Harpal

Background: Pituitary apoplexy is one of the rare endocrine emergencies. Most series indicate that incidence is between 2-7% based on clinical, surgical and histopathological evidence.1-3 Usually presents with severe headaches that may be associated with nausea vomiting, ocular palsies, fever, photophobia. Predisposing factors are pre-existing pituitary conditions, hypertension, major surgery, anticoagulation therapy, pregnancy, radiotherapy. Appropriate endocrine, ...

ea0069oc2 | Oral Communications | SFENCC2020

Paraneoplastic hypoglycaemia secondary to IGF-2 secretion from a metastatic gastrointestinal stromal tumour

Onyema Michael , Drakou Eftychia , Giovos Georgios , Leca Bianca , Ganguly Ratnadeep , Murthy Narasimha , Grossman Ashley , Randeva Harpal , Dimitriadis Georgios

Case history: Herein, we report the case of a 79-year-old male who presented acutely to A&E with recurrent episodes of symptomatic hypoglycaemia. A random glucose at presentation was low at 1.4 mmol/l and upon correction symptoms resolved. While hospitalized, he continued having episodes of symptomatic hypoglycaemia, requiring treatment with intravenous dextrose and per os steroids. Once stable, he was discharged with advice.Investigations: ...