Searchable abstracts of presentations at key conferences in endocrinology

ea0022p835 | Thyroid | ECE2010

Hypothyroidism related to tyrosine kinase inhibitors: an underdiagnosed disorder?

Azevedo Teresa , Martinho Mariana , Martins Teresa , Dias Florbela , Cunha Nuno , Valido Frederico , Gervasio Helena , Rodrigues Fernando

Introduction: Tyrosine Kinase Inhibitors (TKIs) are approved for the treatment of several cancers and can induce hypothyroidism by unclarified mechanisms.Objectives: To assess the prevalence of hypothyroidism in patients treated with TKIs.Methods: Retrospective review of clinical records of patients treated with TKIs in our institution between 2003 and 2009. We evaluated parameters such as sex, oncologic pathology, TKI used, TSH an...