Searchable abstracts of presentations at key conferences in endocrinology

ea0062p72 | Poster Presentations | EU2019

Challenges in managing a young lady with recurrent unexplained hypoglycaemia

Robbins Tim , Murthy Narasimha , Gholap Nitin

Case history: A 23-year-old Caucasian nurse presented with six months of frequent recurrent symptomatic hypoglycaemic episodes with capillary blood glucose ranging between 1.2 and 3.5 mmol/l and symptoms improving after a carbohydrate snack or a drink. The episodes were more likely to occur during fasting state and after excess physical activities. A careful history excluded intake of any off-prescription medications, dfrugs or psychosocial problem.Inves...

ea0077p28 | Bone and Calcium | SFEBES2021

Case Report: Asymptomatic hypercalcaemia in a patient with TB re-activation

Chaudhury Nadia , Thadani Puja , Ladher Ramesh , Cajic Vjeran , Gholap Nitin

Background: Vitamin D is important for calcium homeostasis. In granulomatous diseases including tuberculosis (TB), hypercalcaemia may be seen. Suspected mechanisms include elevated vitamin D sensitivity and increased extrarenal synthesis of 1,25-dihydroxyvitamin D [1,25(OH)2D] by alveolar macrophages within granulomas. Prevalence of hypercalcaemia in TB patients vary worldwide, yet is rare in the UK. We present a case of hypercalcaemia in a patient with TB reactivat...

ea0077p159 | Bone and Calcium | SFEBES2021

Hypercalcaemia as an isolated manifestation of Sarcoid Myositis: A rare case report

Baitule Sudhanshu , Dolan Lauren , Kasavkar Ganesh , Gholap Nitin

Background, case-history: Hypercalcaemia secondary to parathyroid hormone (PTH) independent mechanisms is well known, with differentials including Sarcoidosis. We describe a case of Sarcoid Myositis presenting with symptomatic hypercalcaemia (adjusted serum calcium levels of 3.12 mmol/l) but no muscle weakness in a 39-year-old lady with a background of Type 1 Diabetes Mellitus, Hyperthyroidism, and Rheumatoid Arthritis.Investigations: Laboratory investig...

ea0077p229 | Neuroendocrinology and Pituitary | SFEBES2021

Case report: pituitary metastasis and Its diagnostic complexity

Chaudhury Nadia , Thadani Puja , Awala Orighomisan , Randeva Harpal , Correa Peter , Machenahalli Pratibha , Gholap Nitin

Background: Pituitary metastasis (PM) is a rare occurrence in malignancy, associated with poor prognosis. Only 7% of patients are symptomatic. High index of suspicion and prompt investigation are essential. We report a case of PM, highlighting challenges in diagnosis and management.Case Report: Sixty-six year old male was referred to endocrinology due to headaches and hyponatremia. He had metastatic colorectal carcinoma, treated with bowel, liver and lun...

ea0086p260 | Neuroendocrinology and Pituitary | SFEBES2022

Cushing’s Syndrome – A medical emergency and diagnostic challenge

Thadani Puja , Chaudhury Nadia , Murthy Narasimha , Rao Ranganatha , Randeva Harpal , Weickert Martin , Gholap Nitin

Background: Ectopic CushingÂ’s syndrome (ECS) is a rare and severe condition at times presenting acutely with intense hypercortisolism. The intensity of hypercortisolism can be disproportionate to underlying tumoral condition, and associated life-threatening complications are common arising suddenly. Hypercortisolism must be controlled rapidly pending definitive treatment of tumoral source to avoid life-threatening consequences.Case Summary: 31-year-...

ea0075p09 | Pituitary and neuroendocrinology | EYES2021

Case Report: Pituitary metastasis and its diagnostic complexity

Chaudhury Nadia , Thadani Puja , Awala Orighomisan , Randeva Harpal , Correa Peter , Machenahalli Pratibha , Gholap Nitin

Background: Pituitary metastasis (PM) is a rare occurrence in malignancy, associated with poor prognosis. Only 7% of patients are symptomatic. High index of suspicion and prompt investigation are essential. We report a case of PM, highlighting challenges in diagnosis and management.Case Report: Sixty-six year old male was referred to endocrinology due to headaches and hyponatremia. He had metastatic colorectal carcinoma, treated with bowel, liver and lun...

ea0086p32 | Bone and Calcium | SFEBES2022

Medical optimisation and multidisciplinary approach to management of hyperparathyroid crisis in an elderly patient

Lynn Ko Ye , G Baitule Sudhanshu , Wellala A.V.H. , Iqbal Asif , Davies Joseph , Perkins Ruth , Rao Ranganatha , Basavaiah Natesh , N Gholap Nitin

Primary hyperparathyroidism causing symptomatic hypercalcaemia is often encountered in clinical practice. However, hyperparathyroid crisis is a rare and potentially fatal presentation of primary hyperparathyroidism characterised by profoundly symptomatic hypercalcaemia, altered mental status, and cardiac and renal dysfunction. Recognising the need for rapidly controlling hypercalcaemia with aggressive medical therapy and definitive management with early parathyroidectomy are n...