Searchable abstracts of presentations at key conferences in endocrinology

ea0015p279 | Reproduction | SFEBES2008

A randomised trial comparing a low carbohydrate diet and nutrient-balanced low glycaemic index diet on body weight, hyperandrogenism and cardiovascular risk factors in women with polycystic ovary syndrome (PCOS)

Ghosh Diptendra , Murphy Caroline , Elsheikh Mohgah

PCOS affects ~10% of women of reproductive age and is characterised by hyperandrogenism and ovulatory dysfunction. About 60% of women with PCOS are overweight, with an increased risk of developing type 2 diabetes mellitus.This Local Ethics Committee approved study aimed to determine the optimum composition of a weight reducing diet in management of women with PCOS. It compared the effect of a low carbohydrate with that of a low glycaemic index (GI) diet ...

ea0021p163 | Diabetes and metabolism | SFEBES2009

An exploration of the predictive factors for the early pleiotropic responses to exenatide therapy in patients with type 2 diabetes mellitus

Barber Thomas , Reddy Narendra , Begbie Helen , Sophal Naseem , McCulloch Carol , Rogers Angela , Naziat Auditi , Ghosh Diptendra , Mukhtar Mamoun , Simpson Hugh

Aims: Our aim was to explore predictive factors for the pleiotropic responses to exenatide during the first 12 weeks of therapy, and associations between these responses.Methods: This was an observational study based on patients (n=83) with type 2 diabetes mellitus (T2D) in whom exenatide had been added to existing oral hypoglycaemic therapy. Exenatide was administered subcutaneously (5 mcg bd for the first month, 10 mcg bd thereafter). Data colle...