Endocrine Abstracts

A 36 M seen in endocrinology clinic October 2022 with 9/12 history of reduced testicular size and hypo gonadal symptoms. He has a past medical history of suicidal ideation and urinary incontinence. On review of previous GP records from 2003 he was seen for delayed puberty, although the patient denied this in clinic. There was no history of testicular trauma or infection and he denied any history of exogenous steroid or recreational drug use. There was no significant family his...

Background: HDL is a plasma lipid-protein complex of lipids and alphalipoproteins (apolipoproteins A-I and A-II). It is involved in reverse transport of cholesterol from peripheral tissue to liver, allowing cholesterol degradation. HDL cholesterol (HDL-C) levels are inversely associated with cardiovascular risk. HDL-C levels can be elevated due to genetic causes or drugs. We present a case where significantly raised HDL levels caused some concern at the outset.<p class="ab...

Background: The prevalence of incidental pituitary adenoma is estimated between 10 and 20% in autopsy and radiological data. Such pituitary incidentalomas are increasingly detected, as access to sensitive imaging modalities improves. We present a review of the recent pituitary incidentaloma referrals at a tertiary centre during 2 years from January 2013.Methods: All patients with pituitary incidentalomas on brain imaging between 2013 and 2015 were review...

Aim: Investigation of thyroid nodules usually involves an ultrasound and fine needle aspiration (FNA); however it could still be challenging to devise a management plan based on these. The aim of our study was to compare the reliability of two thyroid FNA’s and ultrasound in comparison to post-operative histology in managing thyroid nodules.Methods: The data on patients who had underwent thyroidectomy and had at least two FNAs and Ultrasound pre-ope...

Aim: The aim of our study was to assess the correlation between pre-operative fine needles aspiration based cytology with post-operative histology in patients with thyroid nodules.Methods: A retrospective analysis of patients who had thyroidectomy (hemi, subtotal, or total) was conducted and information on histology was obtained. Pre-operative FNA (done once or twice) was also obtained and compared with histology. Patients operated for Graves’ disea...

Introduction: Incidental pituitary adenoma (IPA) is found in 10–20% autopsy and radiological series. These are being increasingly detected as access to sensitive imaging modalities improves.Methods: Patients with incidental pituitary findings between 2012 and 2016 were identified from local database. Referral details, clinical features and radiological findings were analysed. A single radiologist reviewed all images to avoid bias.<p class="abste...

Aim: Patients with thyroid nodules, usually undergo FNA, prior to considering surgery however the results may not be conclusive. Our aim is to compare the cytology results in patients who have had two FNA’s with post-operative histology.Methods: All patients who have had thyroidectomy and two pre-operative FNA’s over 7 years were identified. Post-operative histology and FNA cytology was collected from pathology records. Standard ‘Thy’...

A 61 year old female, without significant medical history, presented to her optometrist in Feb 2018 with clouding of vision and left sided proptosis. Opthalmic examination showed vision 6/7.5 right and 6/9 left eye, 3 mm proptosis on the left and diplopia on upward and right lateral gaze. Brain MRI demonstrated 6.3×5.6×5.8 cm lesion centered in the clivus and pituitary fossa, expanding in all directions; the bulk of the lesion was in the left parasellar region, encas...

Aim: The BTA guidelines published recently suggested an uniform U1–U5 classification of thyroid nodules on ultrasound (US) and organising management and follow-up based on these grades. The aim of our retrospective analysis was to assess the reliability and usefulness of US in assessment of thyroid nodules, in comparison with post-operative histological diagnosis.Methods: All patients who underwent thyroid surgery for thyroid nodules were assessed, ...