Endocrine Abstracts

Ghrelin is gastric peptide with appetite stimulating and growth hormone (GH) releasing properties. Circulating ghrelin levels decrease after nutrient ingestion, oral and iv glucose challenge. It has been hypothesized that vagal system may have a major role in initiating this decrease.The aim of this study was to investigate circulating ghrelin levels during oral glucose challenge in gastrectomized (GASTRX)- vagotomized patients. The study was approved by...

Posttreatment assessment of the disease activity and definition of cure of acromegaly, by measuring GH secretion, remains problematic. Furthermore, with our efforts to achieve tight biochemical control of the disease it is foreseeable that a proportion of patients may be rendered GH deficient (GHD). The aim of our study was to evaluate residual GH secretion in cured patients with acromegaly. The study was approved by the Hospital Ethical Committee and after informed consent, b...