Searchable abstracts of presentations at key conferences in endocrinology

ea0002oc12 | Neuroendocrinology | SFE2001

Tissue distribution of the mRNA of the novel endocrine regulator ghrelin and its receptor, GHS-R

Gnanapavan S , Grossman A , Korbonits M

Ghrelin is a novel growth hormone-releasing peptide, recently identified in the rat stomach as the endogenous ligand for the growth hormone secretagogue-receptor (GHS-R). Previously, regulation of GH release was thought to occur primarily via a phasic interaction between two hypothalamic neuropeptides, GHRH and somatostatin. It is now thought that ghrelin is an important third factor in the regulatory pathway. In addition to its GH-releasing activity ghrelin may have other act...