Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep949 | Thyroid | ECE2020

Medullary thyroid cancer follow-up in a tertiary center

Apaydin Tugce , Imre Eren , Gogas Yavuz Dilek

Introduction: Although medullary thyroid cancer (MTC) constitutes 2–4% of all thyroid cancers, it is associated with higher mortality compared to differentiated thyroid carcinomas. Here we present long term clinical results of medullary carcinoma patients’ follow-up in our center.Methods and results: MTC was detected in 27 (3.73%) patients of 850 thyroid cancer cases who were followed-up between 2004 and 2020 at the Marmara University School ...

ea0041ep888 | Pituitary - Clinical | ECE2016

Evaluation of endothelial function and insulin sensitivity in patients with prolactinoma

Buket Bayram F , Tekin Bahar , Gogas Yavuz Dilek

Objective: Hyperprolactinemia has been reported to be associated with endothelial dysfunction, abnormalities of carbohydrate metabolism and insulin sensitivity. The aim of this study was to evaluate carbohydrate metabolism and endothelial function of our patients in outpatient clinics.Material and methods: In this cross-sectional study, currently or previously treated 87 hyperprolactinemic patients with PRL-secreting adenoma (fifty four with microadenoma...

ea0070aep832 | Reproductive and Developmental Endocrinology | ECE2020

Male hypogonadism and sarcopenia

Dinçer Yazan Ceyda , Apaydin Tugce , Gogas Yavuz Dilek

Background and aim: Low testosterone levels are known to be associated with unfavorable body composition and testosterone replacement is known to be associated with increased muscle mass and muscle strength. The aim of this cross-sectionalstudy is to evaluate the grip strength, appendicular muscle mass and physical performance and bone mineral densities of hypogonad male patients.Method: 75 hypogonad and 45 healthy control subjects were included in this ...

ea0081p145 | Pituitary and Neuroendocrinology | ECE2022

The role of advanced glycation end products on vertebral fractures in patients with acromegaly

Melin Uygur Meliha , Dereli Yazıcı Dilek , Gogas Yavuz Dilek

Introduction: Acromegalic osteopathy is an emerging complication characterized by high risk for vertebral fractures (VFS), whereas bone mineral density (BMD) may not be useful to predict the risk. Recent studies have reported that increased advenced glycation end products (AGEs) are associated with bone fragility. We aimed to evaluate the relationship between AGEs and VFs in patients with acromegaly.Study design: Cross-sectionalPat...

ea0090p56 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Long-Term Diabetes Remission Rates In A Group of Type 2 Diabetic Patients After Sleeve Gastrectomy and Rou and Y Bypass Metabolic Surgery: A Single-Centered Experience

Saydam Simge , Tuğberk Bakar Murat , Erol Tuğce , Gogas Yavuz Dilek

Introduction: Various rates were reported regarding diabetes remission and improvement in hyperglycemia in many studies from different populations. Determinants of diabetes remission have not been definitively established so far. In this study, we aimed to evaluate the long-term glycemic status after bariatric surgery in diabetic obese patients followed by Marmara University Endocrinology Outpatient Clinic.Method: The retrospective study included 233 typ...

ea0020p375 | Diabetes and Cardiovascular | ECE2009

ECoRI polymorphism but not XBaI polymorphism of apolipoprotein B gene is associated with carotis intima media thickness in type 2 diabetic patients

Yuksel Meral , Sancak Seda , Yazici Dilek Dereli , Ozben Beste , Gogas-Yavuz Dilek , Akalin Nefise Sema

ApoB plays a central role in lipoprotein metabolism through regulation of total cholesterol and LDL-cholesterol (LDL-C) concentrations in plasma. Two restriction fragment length polymorphisms (ECoRI and XbaI) represent single base alterations in the coding region of ApoB gene. ECoRI polymorphic region of ApoB gene is due to on an amino acid change (Glu→Lys). The XbaI polymorphic region of ApoB gene results from a substitution of (A→T) in the threonine codon and doe...

ea0070aep141 | Bone and Calcium | ECE2020

Identifying clinical characteristics of hypoparathyroid patients in turkey: The ‘HIPOPARATURK-NET Study’

Konca Degertekin Ceyla , Gogas Yavuz Dilek , Pekkolay Zafer , Ugur Kader , Or Koca Arzu , Topaloğlu Ömercan , Ozdemir Kutbay Nilufer , Aydoğan Ünsal Yasemin , Yilmaz Nusret , Omma Tülay

Hypoparathyroidism is a rare endocrine disorder whose epidemiologic characteristics regarding the cause, clinical course, acute and chronic complications have not been well defined. There is also a substantial geographic variability regarding those parameters, and country-specific local data is scarce.This study was conducted to assess the baseline characteristics, including the demographics, etiologic distribution, disease severity, medications use...

ea0070aep182 | Bone and Calcium | ECE2020

Clinical characteristics of subjects with very high serum 25 OH vitamin D levels in turkey: DeVIT-TOX survey

Pekkolay Zafer , Gogas Yavuz Dilek , Sedar Saygili Emre , Topaloğlu Ömercan , Emir Önder Çağatay , Soylu Hikmet , Taskaldiran Isilay , Esen Pazır Ayșe , Ugur Kader , Tanrikulu Seher , Nur Firat Sevde , Meryem Atak Burcu , Batman Adnan , Omma Tülay , Cagiltay Eylem , Ozdemir Kutbay Nilufer , Çetinkaya Altuntaș Seher , Nasiroglu Imga Narin , Karakilic Ersen , Hekimsoy Zeliha , Kılınç Faruk , Yay Adnan , Eroğlu Mustafa , Kemal Tuzcu Alpaslan

Background: Treatment of vitamin D deficiency orinappropriate vitamin D supplementation may cause side effects associated with hypercalcemia. We observed a tendency to use very high single dose cholecalciferol for treatment of vitamin D deficiency.Aim: The primary aim of this study was to examine the clinical characteristics of patientswith very high serum 25OHD levels of vitamin D toxicity in Turkey.Materials and methods: An invit...