Endocrine Abstracts

Introduction: Recent studies indicate that patients diagnosed with adrenal incidentaloma may present with cardiovascular disease. The aim of this study was to investigate markers of subclinical cardiovascular disease in patients with adrenal incidentaloma and healthy control group.Methods: This study included 50 patients with non-functional adrenal adenoma and 30 healthy controls. BMI and waist circumference of the patients were measured. The lipid param...

Based on the effects of Vitamin D on immune system it has been suggested that vitamin D may play a role in the pathogenesis of type I diabetes mellitus (T1D) and other organ specific autoimmune disorders. In our study, we aimed to show the effect of Vitamin D deficiency in the development of newly diagnosed T1D and other autoimmune disease that may associated with T1D such as autoimmune thyroid disease (ATD), celiac disease, Addison’s disease, vitiligo and atrophic gastri...

Introduction: Prolactinomas are the most common pituitary tumors. Macroadenomas are rarely seen. Dopamine agonists such bromocriptin and cabergoline are the preferred treatments for prolactinomas. Herein, we report a patient with macroadenoma whose adenoma has resolved rapidly with cabergoline treatment.Case: A 49 year old male patient evaluated for weakness and headache. After detection of central hypothyroidism he was referred to our department. His pr...

Introduction: Cannabis/marijuana/cannabinoids are the most commonly used illicit drug in the world which can be originated from plants or can be in synthetic forms. Here, an intensive marijuana smoker, 33 years old patient, who has osteoporosis with recurrent pathologic fractures will be presented.Case: Thirty-three-years-old male patient was referred to the our clinics in order to investigate the causes that may lead a pathologic fracture because the pa...

A lactating 31-year-old woman who developed L5 vertebral compression fracture 2 months after the delivery of her first child is presented. Serum concentrations of Ca was 10.24 mg/dl (8.6–10.2 mg/dl), phosphorus was 4.1 mg/dl (2.7–4.5 mg/dl), albumin was 4.6 mg/dl, ALP was 210 U/l (35–105 U/l), PTH was 13.8 pg/ml (15–65). There was axial osteoporosis, as assessed by dual-energy X-ray absorptiometry. Z score; L1 (−3), L2 (−3.8), L3 (&#872...

Background: Paget’s disease may affect as many as 3% of adults older than 40 years of age; it is often asymptomatic and usually progresses slowly. Paget’s disease affects men and women almost equally, but men tend to be more symptomatic. The disease is usually not clinically apparent until age 50–60 years. It usually progresses slowly and does not develop in new sites. Many different bones can be affected, and the lesions can vary from single, monostotic lesions...

Background: Bilateral micronodular adrenal cortical disease (miBACD) is a rare and difficult-to-manage disease. miBACD is one of the causes of Cushing’s syndrome. miBACD is divided into primary pigmented nodular adrenocortical disease (PPNAD) and isolated micronodular adrenocortical disease. Its more common presentation is familial PPNAD, as part of Carney syndrome. We also presented a rare case of miBACD.Case presentation: A 20-year-old female pati...

Denosumab is a monoclonal antibody against RANKL used in the treatment of postmenopausal osteoporosis. RANK/RANKL/OPG cycle is effective on both immune system and osteoporosis. Some RANK mutations are associated with hypogammaglobulinaemia. There are studies suggesting that the RANK/RANKL pathway may mediate the development of insulin resistance and hepatosteatosis. However, the clinical effects of denosumab on inflammation and immunity are not well known. In this study, we ai...

Introduction: Thyroid nodules are common in population. High resolution ultrasound and fine needle aspiration biopsy (FNAB) are advised as the first line diagnostic methods. Bethesda classification system is used to provide standardization of cytologic reports. We aimed to evaluate ultrasound guided FNAB results in a mild-to-moderate iodine deficient city of Turkey.Methods: The patients (n=520), who underwent FNAB between December 2011 and Decem...

Introductıon: Pheochromocytoma is a tumor originating from the chromaffin cells. These tumors secrete catecholamines which act on target organs and cause hypertensive crises. They are rare during pregnancy, and a differential diagnosis must be carried out mainly with pregnancy-induced hypertension.Case: A 27-year-old patient in week 17 of pregnancy admitted to our clinic with hypertension and 45×55 mm heterogeneous nodular lesion in left surren...