Searchable abstracts of presentations at key conferences in endocrinology

ea0086p114 | Neuroendocrinology and Pituitary | SFEBES2022

Skull base lymphoma causing hypopituitarism

Shah Preet , Gonzalez Susana

A 69-year-old lady presented to the ophthalmologists in view of a right 6th cranial nerve palsy and headache. Neuroimaging showed a central and right sided base of skull tumour with involvement of multiple cranial nerves (3rd, 4th, 6th). An endoscopic biopsy was inconclusive. She presented to the medical team few days later with drowsiness, lethargy, and her sodium was found to be 117 mmol/l with a potassium of 5.5 mmol/l. Serum osmolality was 267 mOsm/kg, urine osmolality was...

ea0025p4 | Bone | SFEBES2011

Management of hypovitaminosis D in patients with primary hyperparathyroidism

Rathi Manjusha , Gonzalez Susana , Peacey Steve

Epidemiological studies suggest that hypovitaminosis D is common in patients with primary hyperparathyroidism (PHPT). They have higher levels of serum parathyroid hormone (PTH) and markers of bone turnover, and more frequent fractures than vitamin D replete patients. There are concerns that vitamin D repletion in these patients might exacerbate pre-existent hypercalcaemia, although recent literature suggests this is uncommon.We aimed to determine the eff...

ea0013oc15 | Clinical and translational endocrinology | SFEBES2007

Biological variability of insulin resistance in polycystic ovarian syndrome after treatment with Metformin, Orlistat and Pioglitazone

Wei Cho Li , Gonzalez Susana , Holding Stephen , Kilpatrick Eric , Atkin Stephen

Background: A previous study suggested an increased absolute and intraindividual variability of insulin resistance (IR) in overweight women with polycystic ovarian syndrome (PCOS) which may contribute to the increase in cardiovascular risk. There had been no previous data on the change in variability of IR in PCOS with treatment.Methods: PCOS women were recruited using the Rotterdam criteria [mean age (±S.E.M.) 26.4(±1.5)yrs and ...

ea0081p417 | Pituitary and Neuroendocrinology | ECE2022

Terlipressin induced acute severe hyponatremia

Pla Peris Begona , Castro de la Vega Iciar , Roxana Padilla Segura Mayet , Serisuelo Meneu Esther , Abellan Galiana Pablo , Maravall Javier , Perez Naranjo Susana , Gonzalez Boillos Margarita , Angel Merchante Alfaro Agustin

Introduction: Terlipressin is a non-selective vasopressin analogue used in patients with decompensated cirrhosis, gastrointestinal haemorrhage or hepatorenal syndrome. It directly binds to V1 receptors improving circulatory volume by causing splanchnic vasoconstriction and portal hypertension inhibition, and has a full V2 receptor agonism in the collecting duct. In consequence, it increases reabsorption of water and can lead to a decrease in plasma osmolality and hyponatremia....