ea0029p361 | Clinical case reports - Pituitary/Adrenal | ICEECE2012
Denes J.
, Kovacs G.
, Patocs A.
, Glaz E.
, Mezosi E.
, Hubina E.
, Kovacs L.
, Gorombey Z.
, Czirjak S.
, Korbonits M.
, Goth M.
Familial isolated pituitary adenoma (FIPA) occurs if two or more members of a family develop pituitary adenoma with no features of multiple endocrine neoplasia type 1 or Carney complex. FIPA is an autosomal dominant disease with incomplete penetrance. FIPA families can be divided into two distinct groups based on genetic and phenotypic features. In 20% of FIPA families mutations have been identified in the aryl hydrocarbon receptor interacting protein (AIP) gene. The AIP-posit...