Endocrine Abstracts

Context: Hyperglycemia is common among patients with and without diabetes mellitus (DM) hospitalized for infectious diseases. The long-term outcomes of hyperglycemia have not been adequately studied in this population.Objective: Examine the prognostic implications of hyperglycemia and the importance of glycemic control in patients with and without DM during hospitalization for infectious diseases.Methods: Historical prospectively c...

The effect of mTOR inhibitors on pituitary tumors is unknown. Akt overexpression was demonstrated in pituitary adenomas, which may render them sensitive to the antiproliferative effects of these drugs.To evaluate the in vitro effects of mTOR inhibitor rapamycin, and its orally-bioavailable analog RAD001 on pituitary cells, GH3 cells, a mammosomatotroph rat pituitary tumor cell line, and human GH-secreting and non-functioning pituitary adenoma (NFP...

Background: Glucose variability (GV) is common among hospitalized patients but the prognostic implications among patients hospitalized to surgical wards are unknown.Objective: Investigate the association between GV, length of stay (LOS) and mortality.Methods: Historical prospectively collected data of patients ≥18 years, hospitalized to general surgery wards between January 2011–December 2017. GV was assessed by coeffici...