Searchable abstracts of presentations at key conferences in endocrinology

ea0009p104 | Endocrine tumours and neoplasia | BES2005

Acromegaly outcomes: the Exeter experience

Goss L , Forbes M , Macleod K , Daly M , Donohoe M , Hattersley A , Vaidya B

Aim: To audit the management and treatment outcomes of patients with acromegaly at Royal Devon and Exeter Hospital.Patients and methods: Hospital case records of 43 patients (21 male), presenting between 1982 and 2004 were reviewed retrospectively. Age at presentation ranged from 21 years to 77 years, with average follow-up being 11.2 years.Results: 9 (29 percent) of 31 patients had microadenomas at presentation while 22 (71 percen...

ea0009p220 | Clinical | BES2005

Unusual presentation of multiple endocrine neoplasia 2A

Saravanan P , Goss L , Dunn J , Paisey R , Rankin J , MacLeod K

Multiple Endocrine Neoplasia 2 (MEN2) is a rare, autosomal dominant neuroendocrine tumour. MEN2A is a syndrome of medullary thyroid carcinoma (MTC), pheochromocytoma and parathyroid tumours. MEN2B is characterised by MTC, pheochromocytoma, marfanoid habitus and intestinal & mucosal ganglioneuromas. MEN2 syndromes are due to mutations in the RET proto-oncogene, located near the centromere of the chromosome 10. While the commonest mutations described in MEN2A is in exon 11 (...