ea0081rc4.2 | Rapid Communications 4: Pituitary and Neuroendocrinology 1 | ECE2022
Stelmachowska-Banas Maria
, Ostrowska Magdalena
, Goszczyński Tomasz
, Kowalski Konrad
, Korbonits Marta
, Kapuścińska Renata
, Zgliczyński Wojciech
, Glinicki Piotr
Introduction: Hormone macromolecules are complexes of hormones with other compounds, most often with IgG immunoglobulin. They show variable immunoreactivity in immunochemical tests (IRMA, ELISA, CLIA, ECLIA) and usually have a weak biological effect. They can interfere with immunological assays of various hormones. Some known hormone macrocomplexes are: BB-PRL (24% - 34%), macro-TSH (0.6% - 1.2%) and very rare macromolecules of various hormones: calcitonin, PTH, insulin (singl...