Endocrine Abstracts

Introduction: With the onset of puberty blood pressure increases more in men than in women while boys and girls do not show any gender differences in blood pressure. Androgens are known to play an important role in renal tubular epithelial cell growth, hypertrophy and erythropoetin production and may be important determinants of sex-specific differences in blood pressure. However, the exact mechanisms are not clear yet.Methods: Male Wistar rats aged 8&#1...

Introduction: Androgens are known to play an important role in renal tubular epithelial cell growth, hypertrophy and erythropoetin production, however the exact mechanisms are not clear yet. 5alpha-dihydrotestosterone is synthesized primarily in gonads and skin, and is the most used androgen in studies. However, little is known about testosterone effects in non-gonadal tissues.Methods: Male Wistar rats aged 8–10 weeks were orchiectomized and put on ...