Searchable abstracts of presentations at key conferences in endocrinology

ea0011p292 | Diabetes, metabolism and cardiovascular | ECE2006

Glucose metabolism, insulin secretion and insulin sensitivity in juvenile hemochromatosis

Angelopoulos N , Noutsou M , Goula A , Tolis G

Among specific diabetes subtypes secondary to pancreatopathies, hereditary hemochromatosis is an inherited disorder of iron metabolism, resulting to excessive iron overload and tissue damage in various organs. We report here the case of a man with the young-onset form of the disease and we describe his glycaemic status, before and during venesection therapy. A 25-year-old man attended our clinic in Athens, Greece, with hypogonadotropic hypogonadism due to hereditary hemochroma...

ea0011p436 | Endocrine disruptors | ECE2006

Loss and resumtion of ovarian function after mitotane administration

Kostoglou-Athanassiou I , Goula M , Athanassiou P , Kaldrymidis Ph

The adrenolytic agent mitotane [o,p’-DDD or 1,1-(o,p’-dichlorodiphenyl)-2,2-dichloroethane] is a derivative of the insecticide DDT and is used for the treatment of adrenal carcinoma. It induces necrosis and atrophy of the adrenal cortex. Estrogenic action after single exposure but intense antiestrogenic action after repeated exposure of porcine ovarian follicles has been observed in vitro (Wojtowicz et al. 2004).The aim of the stu...