Searchable abstracts of presentations at key conferences in endocrinology

ea0065p217 | Metabolism and Obesity | SFEBES2019

A novel method for analysis of 11 oestrogens using high-throughput liquid chromatography tandem mass spectrometry

Gilligan Lorna , Goymer Lauren , Toor Harjeavon , Cox Grace , Shaheen Fozia , Arlt Wiebke , Taylor Angela

Oestrogen quantification in serum is challenging as concentrations are low, especially in men and post-menopausal women. Additionally, oestrogens do not ionise readily and structure similarities can lead to cross-reactivity and reduced specificity, especially with immunoassay. Full characterisation of oestrogen metabolism and its role in disease progression has therefore not been fully investigated. We aimed to develop and validate a liquid chromatography mass spectrometry met...