Searchable abstracts of presentations at key conferences in endocrinology

ea0014p283 | (1) | ECE2007

In vitro effects of 17 βE2 and raloxifene on desmoid tumour derived cells

Picariello Lucia , Sala Silvia Carbonell , Martineti Valentina , Gozzini Alessia , Brandi Maria Luisa , Tonelli Francesco

Desmoid tumours (DT) are a benign manifestation of familial adenomatous polyposis. The prevalent development in young fertile women, the regression during menopause or with tamoxifen treatment, underlie the potential role of estrogens and Estrogen Receptors (ERs) in the pathogenesis of these tumors. To investigate this hypothesis, the expression of ERs α and β in desmoid tumors derived cell cultures, the effects of 17βE2 and of raloxifene on DT cell p...