Searchable abstracts of presentations at key conferences in endocrinology

ea0049gp215 | Thyroid 2 | ECE2017

Hypothyroidism and heart failure outcome: a study with a long-term follow-up

Triggiani V , Licchelli B , Rizzo C , Grande D , Terlizzese P , Leopizzi T , Gioia I , Giagulli VA , Guastamacchia E , Iacoviello M

Background: Hypothyroidism (HT) has been demonstrated to be associated to heart failure (HF) progression.Aim of the study: To evaluate the impact of HT on the progression of HF during a long-term follow-up.Methods: From 2006 to 2015, we evaluated 675 consecutive CHF outpatients (523 males, 64±13 years) in stable clinical conditions (>1 month) and in conventional therapy. They underwent a clinical evaluation, 12-lead ECG, e...

ea0029p1022 | Male Reproduction | ICEECE2012

Effect of testosterone on seminal proteome in male hypogonadism

Milardi D. , Grande G. , Vincenzoni F. , Giampietro A. , Bianchi A. , Messana I. , Pontecorvi A. , Marinis L De , Castagnola M. , Marana R.

Seminal plasma (SP) contains proteins secreted by testis, epididymis and male accessory glands, involved in the successful fertilization of the oocyte. The function of epididymis, prostate and seminal vesicles are dependent upon the presence of androgenic stimuli.To investigate the role of testosterone in the modulation of the proteomic pattern in SP, we analyzed human SP proteome comparing the panel of common seminal proteins in five fertile normogonada...

ea0049gp214 | Thyroid 2 | ECE2017

Thyroid hormones deficiencies and poor outcome in chronic heart failure outpatients

Triggiani Vincenzo , Licchelli Brunella , Terlizzese P , Grande D , Rizzo C , Lattarulo MS , Leopizzi T , Gioia I , Angelo Giagulli Vito , Guastamacchia Edoardo , Iacoviello Massimo

Background: Hypothyroidism and low T3 syndrome frequently occur in HF patients.Aim of the study: To evaluate in a large sample of CHF patients the association between thyroid hormone deficiencies and poor outcome.Methods and results: From 2006 to 2015, we screened 712 consecutive CHF outpatients (551 males, 64±14 years, left ventricular ejection fraction (LVEF) 33±10%, NYHA class 2.3±0.6, NTproBNP 2153±4696 pg/m...

ea0049gp216 | Thyroid 2 | ECE2017

The correction of TSH with thyroid replacement therapy is associated with a better outcome in chronic heart failure patients

Triggiani V , Licchelli B , Grande D , Rizzo C , Terlizzese P , Giagulli VA , Lattarulo M.S , Leopizzi T , Gioia I , Guastamacchia E , Iacoviello M

Background: It has been previously demonstrated that thyroid hormone deficiency is associated with a worse outcome in patients affected by chronic heart failure (CHF). However, few data are available about the effects of thyroid replacement therapy on the prognosis of patients.Aim of the study: The aim of the study was to evaluate the relationship among thyroid replacement therapy, correction of thyroid stimulating hormone (TSH) serum levels and outcome ...