Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep67 | Adrenal and Cardiovascular Endocrinology | ECE2020

Hyperparathyroidism in patients with overt and mild primary aldosteronism: Epidemiological data from a tertiary centre

Gravvanis Christos , Papanastasiou Labrini , Glikofridi Spyridoula , Voulgaris Nikolaos , Tyfoxylou Ernestini , Kounadi Theodora

Introduction: Primary aldosteronism (PA) is the most common cause of endocrine hypertension. In recent studies, increased prevalence of hyperparathyroidism (HP) has been observed in PA patients. However, the prevalence of HP in overt or milder forms of PA has not been evaluated yet.Objectives: To estimate the prevalence of HP in patients with PA (overt and milder forms) and investigate the effect of treatment (eplerenone or surgery) on PTH secretion....

ea0070aep360 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Arare case of caucasian patient with insulin autoimmune syndrome induced by a-lipoic acid

Glikofridi Spyridoula , Papanastasiou Labrini , Markou Athina , Andrianesis Vasileios , Gravvanis Christos , Kounadi Theodora

Introduction: Insulin autoimmune syndrome (IAS) is characterized by spontaneous hypoglycemia caused by insulin autoantibodies (IA) in the absence of exogenous insulin administration. The occurrence of IAS may be influenced by a genetic predisposition determined by HLA class II. IAS is frequently reported in Japanese and Koreans due to their genetic predisposition (HLA-DRB1*0406) rather than in the Caucasians. Some drugs containing sulfhydryl compounds are known to initiate the...

ea0063p91 | Calcium and Bone 1 | ECE2019

Effectiveness of intramuscular Ergocalciferol treatment in a patient with o steomalaciadueto severe vitamin D deficiencyafterbariatric surgery

Papanastasiou Labrini , Gravvanis Christos , Tournis Symeon , Markou Athina , Kalantzi Athanasia , Zoulias Manolis , Georgakopoulou Georgia , Pagoni Stamatina , Kounadi Theodora

Bariatric surgery is a common treatment for morbidly obese patients requiring weight loss and/or metabolic control. Vitamin D (VitD) deficiency and bone loss may occur post-operatively and supplementation with high oral doses of Vitamin D is required. Alternatively, intramuscular depot ergocalciferol (vitamin D2) which slowly releases VitD and overcomes the gastrointestinal tract, could be administrated in such patients.Aim: To present a case of severe V...

ea0070aep63 | Adrenal and Cardiovascular Endocrinology | ECE2020

Surgical outcomes of adrenalectomy for primary hyperaldosteronism after using novel diagnostic tests

Alexandraki Krystallenia , Markou Athina , Papanastasiou Labrini , Tyfoxylou Ernestini , Kapsali Chara , Gravvanis Christos , Kaltsas Gregory , Zografos Giorgos , Piaditis George

Background: Primary hyperaldosteronism (PHA) is the most frequent type of endocrine hypertension with a prevalence that is continuously rising. Following the introduction of diagnostic tests that consider both the adrenocorticotropic hormone effect andrenin–angiotensin–aldosterone system (RAAS), the post-dexamethasone saline infusion test (D-SIT) and the overnight dexamethasone, captopril, valsartan test (DCVT) using pharmaceutical RAAS blockade, a higher prevalenc...

ea0073oc1.4 | Oral Communications 1: Adrenal and Cardiovascular Endocrinology | ECE2021

The impact of targeted treatment on echocardiographic indices in patients with overt and mild primary aldosteronism, compared to patients with essential hypertension.

Gravvanis Christos , Papanastasiou Labrini , Kaoukis Andreas , Glikofridi Spyridoula , Monastirioti Nicoleta , Voulgaris Nikolaos , Ernestini Tyfoxylou , Markou Athina , GeorgePiaditis

IntroductionPrimary aldosteronism (PA) is associated with cardiovascular events and target organ damage, such as left ventricular (LV) hypertrophy and cardiac dysfunction. However the impact of subtle aldosterone secretion on cardiac function has not yet been evaluated.AimTo prospectively evaluate the cardiac function using echocardiographic indices in patients with biochemical overt, mild PA and essential hy...

ea0063p475 | Calcium and Bone 2 | ECE2019

McCune-Albright syndrome: report of two cases

Kalantzi Athanasia , Giagourta Eirini , Tournis Simeon , Papanastasiou Labrini , Gravvanis Christos , Glykofrydi Spyridoula , Chantziara Maria , Theodoropoulou Georgia , Patikos Christos , Georgakoulias Nikolaos , Kounadi Theodora

Introduction: McCune-Albright syndrome (MAS) is a rare non-inheritable genetic disease. It is attributed to an early embryonic postzygotic somatic activating mutation of GNAS, leading to a mosaic that causes polyostotic fibrous dysplasia, café au lait macules and polyendocrinopathy.Aim: To present two cases of this rare syndrome.Case report: A 38-year-old male patient presented with a bone lesion of the forehead and acromegali...

ea0063ep18 | Adrenal and Neuroendocrine Tumours | ECE2019

Characteristics, management and outcome of patients with adrenocortical carcinoma in a tertiary hospital: a retrospective study

Papanastasiou Labrini , Choreftaki Theodosia , Zografos George , Kapsali Chara , Kalantzi Athanasia , Monastirioti Nikoleta , Gravvanis Christos , Glykofridi Spyridoula , Tyfoxilou Ernestini , Vlaxou Sofia , Charalampidou Liana , Voulgaris Nikos , Markou Athina , Giagourta Irini , Piaditis George , Kounadi Theodora

Adrenocortical carcinoma (ACC) is a rare, aggressive tumor with poor prognosis, affecting 0.5–2 cases/106population/year.Objective: To analyse retrospectively characteristics, management and outcome of ACC patients, followed in our center between 2010–2018.Material and methods: The medical records related to diagnosis, treatment and follow-up of nine patients of 59.2±13.8 years with histological diagnosis ...

ea0056p20 | Adrenal cortex (to include Cushing's) | ECE2018

Prevalance of primary aldosteronism in hypertensive patients: epidemiological data from a tertiary centre

Voulgaris Nikolaos , Papanastasiou Labrini , Vlachou Sofia , Kyriazi Evangelia , Tyfoxylou Ernestini , Monastirioti Nikoletta , Kapsali Chara , Charalampidou Liana , Aglaia Zachaki , Kalantzi Athanasia , Gravvanis Christos , Markou Athina , Giagourta Eirini , Kounadi Theodora , Kassi Eva , Kaltsas Gregory , Piaditis George

Introduction: Primary aldosteronism (PA) is the most common cause of endocrine hypertension. Its prevalence varies from 5-15%, which depends mainly on the cut-offs of the diagnostic tests.Aim: To estimate the prevalence of PA in patients with different stages of hypertension based on a dynamic overnight diagnostic test.Methods: One hundred ninety nine hypertensive patients were divided in 3 groups according to the stage of hyperten...

ea0099p418 | Adrenal and Cardiovascular Endocrinology | ECE2024

Appraisal of modified tests for the diagnosis and treatment of primary aldosteronism: A single endocrine center experience

Markou Athina , Kaltsas Gregory , Papanastasiou Labrini , Voulgaris Nikolaos , Gouli Aggeliki , Tsiavos Vaios , Gravvanis Christos , Tyfoxylou Ernestini , Vlachou Sofia , Kapsali Chara , Giagourta Irini , Kounadi Theodora , Vamvakidis Kyriakos , Zografos George , Chrousos George , Piaditis George

Introduction: Primary aldosteronism (PA), the most common endocrine cause of secondary hypertension, is generally underdiagnosed using current diagnostic tests.Aim: To present our 14-year experience of prospective studies on the diagnosis, prevalence and treatment of PA.Patients and methods: We studied 992 hypertensive patients and 278 age-, sex- and body mass index – matched controls (194 normotensive and 104 with essential h...