Searchable abstracts of presentations at key conferences in endocrinology

ea0020oc2.1 | Diabetes & Obesity | ECE2009

ESE Young Investigator Award

Dirice Ercument , Sanlioglu Ahter Dilsad , Kahraman Sevim , Omer Abdulkadir , Balci Mustafa Kemal , Griffith Thomas S , Sanlioglu Salih

Background: Because type 1 diabetes (T1D) results from the T cell-mediated destruction of the insulin-producing pancreatic beta cells, the depletion of the autoreactive T cells via apoptosis represents a viable strategy for the prevention of autoimmune diabetes. The functional role TNF Related Apoptosis Inducing Ligand (TRAIL), a novel member of TNF superfamily, in autoimmune diabetes remains unknown. To understand this, TRAIL function was counteracted by an injection of solub...