Endocrine Abstracts

Objectives: To study the direct effects of fatty acids (FA) and the involvement of the TLR-4/NFκB pathway with respect to the secretion of adipokines and chemokines from adipocytes.Research design and methods: 3T3-L1 adipocytes were stimulated with increasing doses of FA. The secretion of adiponectin, resistin and MCP-1 was measured by ELISA. NFκB p65 nuclear translocation and TLR-4 expression were investigated by Western blot analysis. NF&#954...