Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep102 | Adrenal and Cardiovascular Endocrinology | ECE2020

Is glucocorticoid replacement therapy in adrenal insufficiency a risk factor for liver steatosis?

Meyer Gesine , Gruendl Madeleine , Schlereth Florian , Gerber Ludmila , Badenhoop Klaus , Bojunga Joerg

Introduction: Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease affecting up to 30% of the population in western countries. Previous studies have demonstrated that increased glucocorticoid levels play an important role in the development of obesity, hyperglycemia, dyslipidemia, insulin resistance, as well as NAFLD. However, the effects of glucocorticoid substitution on the liver in patients with primary or secondary adrenal insufficiency have been rare...