Searchable abstracts of presentations at key conferences in endocrinology

ea0022p405 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Cinacalcet hydrochloride effectively controlled primary hyperparathyroidism in patients unresponsive to bisphosphonates

Faggiano Antongiulio , Somma Carolina Di , Milone Francesco , Ramundo Valeria , Rota Francesca , Vuolo Laura , Guerra Ermelinda , Colao Annamaria

Context: Until now the role of medical therapy in patients with primary hyperparathyroidism (PHP) was mainly based on the use of bisphosphonates. Recently, cinacalcet hydrochloride was reported to be effective in control hypercalcemia in PHP. The aim of this study was to evaluate the efficacy of cinacalcet in PHP patients who were not effectively controlled with alendronate.Patients and methods: Fourteen PHP patients (mean age 64.1±2.6) were include...

ea0016s30.5 | Clinical highlights | ECE2008

Increased prevalence of tricuspid regurgitation in patients with prolactinomas chronically treated with cabergoline: dose and treatment duration effect

Colao Annamaria , Galderisi Maurizio , Sarno Antonella Di , Pardo Moira , Gaccione Maria , D'Andrea Marianna , Pivonello Rosario , Guerra Ermelinda , Lerro Giuseppe , Lombardi Gaetano

Background: Cabergoline, a dopamine receptor-2 agonist, used to treat prolactinomas was associated with increased risk of cardiac valve disease.Objective: To evaluate prevalence of cardiac valve regurgitation in patients with prolactinomas treated with cabergoline.Design: Open, case–control, prospective.Patients: Fifty patients (44 women, 6 men) and 50 sex- and age-matched control subjects.<p class="...

ea0014p14 | (1) | ECE2007

Role of growth hormone/insulin like growth factor 1 system in the remodelling process of the right ventricle in top levels rowers

Vitale Giovanni , Galderisi Maurizio , Colao Annamaria , Innelli Pasquale , Guerra Germano , Guerra Ermelinda , Lloyd Dini Frank , Soscia Antonio , de Divitiis Oreste , Lombardi Gaetano

The intensive physical activity is often associated with cardiac changes, particularly involving the right ventricular (RV) chamber. However, the molecular mechanisms involved in the RV physiologic adaptation to long-term training are not completely understood. In the present study we investigated the role of the growth hormone/insulin like growth factor 1 (GH/IGF-1) axis in the RV remodeling of athletes.Nineteen male top levels rowers and 19 age-matched...