Searchable abstracts of presentations at key conferences in endocrinology

ea0063p186 | Diabetes, Obesity and Metabolism 1 | ECE2019

Relationship between cortisoluria and the presence of metabolic syndrome among HIV-infected patients

Guerreiro Vanessa , Sergio Joao , Serrao Rosario , Sarmento Antonio , Carvalho Davide , Freitas Paula

Introduction: People living with human immunodeficiency virus (HIV) are at increased risk of developing metabolic disorders, such as obesity, dyslipidemia, insulin resistance, diabetes and hypertension; which may also be associated with hypercortisolism. Due to the similarity between the metabolic changes present in these two clinical situations, several studies have evaluated whether HIV-infected patients have increased levels of cortisol, but the results are not consensual. ...

ea0056gp126 | Endocrine Case Reports | ECE2018

Acromegaly and acromegaloidism, two rare insulin-resistance conditions in one patient: reason for GH-IGF-1 discrepancy?

Freitas Paula , Guerreiro Vanessa , Bernardes Irene , Pereira Josue , Silva Roberto Pestana , Fernandes Susana , Carvalho David

Introduction: Lipodystrophies are a group of genetic or acquired diseases characterized by abnormal adipose tissue deposition, frequently associated with insulin resistance, diabetes mellitus, dyslipidaemia, hypertension and hepatic steatosis. Congenital generalized lipodystrophy (LCG) is a well-defined syndrome with autosomal recessive heredity, prevalence <1:10million, with about 400 cases being described. Extreme shortage of subcutaneous adipose tissue, muscle hypertrop...

ea0056p607 | Obesity | ECE2018

Prevalence of obesity in a population of patients with HIV: relationship with clinical lipodistrophy, effect of sex, age, viral replication, duration of disease and cart

Guerreiro Vanessa , Neves Joao , Serrao Rosario , Sarmento Antonio , Carvalho David , Freitas Paula

Introduction: Adipose tissue disturbances (lipodystrophy and obesity) are prevalent in patients infected with HIV. Our aims were to evaluate the prevalence of obesity and the association with lipodystrophy, the effect of gender, age, viral replication, duration of disease and cART in a population of HIV patients under cART.Methods: In this retrospective study, 580 patients were included. The characteristics of the population are presented through percent...

ea0070aep393 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

2-hr vs 1-hr glucose tolerance testing for pre-DM diagnosis, among HIV-infected patients

Guerreiro Vanessa , Cristina Santos Ana , Serrão Rosário , Sarmento António , Carvalho Davide , Freitas Paula

Introduction: Plasma glucose concentration at 1h(1hPG) during an oral glucose tolerance test(OGTT) may be a better predictor of future diabetes mellitus(DM) than 2-h post load glucose concentration(2hPG). HIV-infected individuals may have differential risk of DM compared to the general population, and the optimal diagnosis algorithm for DM in HIV-infected persons remain unclear. We evaluated the agreement of the methods 1 hPG vs 2 hPG) for the diagnosis of pre-D...

ea0070ep447 | Thyroid | ECE2020

Mixed medullary-papillary thyroid carcinoma with mixed lymph node metastases

Guerreiro Vanessa , Costa Cláudia , Oliveira Joana , Santos Ana Paula , Farinha Mónica , Freitas Paula , Torres Isabel

Introduction: Medullary thyroid carcinoma (MTC) and papillary thyroid carcinoma (PTC) are two distinct neoplasms originating from follicular and parafolicular-C cells, respectively. These pathologies have always been considered different from each other in terms of their incidence, their cell origin and their histopathological features. Concurrent occurrence of MTC and PTC in the same patient is an unusual event and its occurrence as true mixed medullary-follicular-derived car...

ea0090ep596 | Endocrine-related Cancer | ECE2023

Case Report: Successful treatment of an atypical lung neuroendocrine neoplasm with PRRT

Guerreiro Vanessa , Lucena Ines , Paula Santos Ana , Prospero Ines , Ferreira Goncalo , Gil Santos Sara , Oliveira Joana , Freitas Paula , Torres Isabel , Duarte Hugo

Neuroendocrine neoplasms (NENs) arise from specialized cells called neuroendocrine cells spread through the body, mainly in the gastrointestinal tract, pancreas and lung. Pathological classification of Lung NENs include well differentiated NENs, that can be classified as typical or atypical carcinoids, and poorly differentiated neuroendocrine carcinomas (NECs), classified as small-cell lung carcinoma (SC-NEC) or large-cell neuroendocrine carcinoma (LC-NEC). We present a case o...

ea0070aep290 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Magnesium supplementation and higher magnesium levels in T2DM patients are associated with better glycemic control and higher rates of total and partial remission post-bariatric surgery

Silva Maria , Mendonça Fernando , João Fonseca Maria , João Ferreira Maria , Salazar Daniela , Pedro Jorge , Guerreiro Vanessa , Sergio Neves João , Lau Eva , Belo Sandra , Varela Ana , Freitas Paula , Carvalho Davide

Introduction: Magnesium (Mg) is an essential mineral for human health. Chronic Mg2+ deficiency and low Mg2+ dietary intake have been associated with increased risk of T2DM. Despite the increased risk of T2DM associated with Mg2+ deficiency; T2DM is often accompanied by hypomagnesemia, especially in patients with poorly controlled glycemic profiles.Bariatric surgery remains the most effective long-term therapy for the management of patients wi...

ea0070aep378 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Bariatric surgery impact on cardiovascular risk factors: Is age a factor to consider?

Mendonça Fernando , Silva Maria , João Ferreira Maria , Salazar Daniela , Guerreiro Vanessa , Pedro Jorge , Sergio Neves Joao , Viana Sara , Belo Sandra , Varela Ana , Freitas Paula , Carvalho Davide

Introduction: Despite the abundance of data addressing the influence of patient’s age on surgery-related complications, its impact on several cardiovascular risk factors following bariatric surgery has been overlooked.Methods: Retrospective unicentric study of 1728 obese patients who underwent bariatric surgery between January/2010 and June/2015. Patients were divided in three groups, according to their age at surgery: <40 (n = 751...

ea0090ep286 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

Prediabetes remission after bariatric surgery: A 4-years follow-up study

Borges-Canha Marta , Neves Joao Sergio , Silva Maria , Mendonca Fernando , Moreno Telma , Ribeiro Sara , Vale Catarina , Goncalves Juliana , Ferreira Helena Urbano , Santos Sara , Calheiros Raquel , Meira Ines , Menino Joao , Guerreiro Vanessa , Pedro Jorge , Varela Ana , Souto Selma , Lima da Costa Eduardo , Freitas Paula , Carvalho Davide , Group CRIO

Background: Bariatric surgery leads to weight loss and to cardiometabolic risk improvement. Although prediabetes remission after bariatric surgery is biologically plausible, data on this topic is scarce.Aim: We aimed to access pre-diabetes remission rate and clinical predictors of remission in a 4 year follow up period.Methods: Observational longitudinal study including patients with morbid obesity and prediabetes submitted to bari...