Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep964 | Pituitary - Clinical | ECE2017

Pregnancy in Cushing’s disease after treatment with surgery and cyber-knife radiosurgery

Oruk G Gonca , Olmezoglu Ali , Apaydin Melda , Guvenc Gonul

Women affected by CushingÂ’s disease (CD) are often infertile due to abnormal follicular development or anovulation. In these patients, first line treatment is pituitary surgery, which is effective in more than 83% of cases with microadenomas, but only in about 35% of those with macroadenomas. When surgery do not normalize circulating ACTH and cortisol concentrations, such drugs, e.g. ketoconazole or metirapone, and radiotherapy are used as adjuvant treatment. Concerning r...