Endocrine Abstracts

IntroductionPheochromocytomas (PHEO) and paragangliomas (PGL) are rare neuroendocrine tumors of the autonomic nervous system, originating from neural crest. Despite the same embryological origin, there are some differences between them.AimWe searched for differences in method of discovery, clinical and biochemical phenotype, of sporadic vs hereditary PHEO/PGL in a cohort of Flemish patients.<p class="abst...

ObjectivesThe European Network for Investigation of Gender Incongruence (ENIGI) is a multicenter prospective cohort study. All participants receive a standardized gender affirming treatment (GAHT) protocol including regular follow-up. The current study compared changes in androgens upon starting GAHT and during follow-up in transgender women (TW) with or without gonadectomy by investigating serum total testosterone (TT), calculated free testosterone (cFT...

In mammals, the gonads and the brain develop from bipotential organs that will differentiate into female or male organs, during a critical period of development. This process begins with the production of testosterone by the testes, which will be converted into estradiol in the brain, by the aromatase. While the end is defined by the moment when the inhibition of androgens (in males), or treatment with estrogens (in females), stops having an effect on brain dimorphism. But in ...