Searchable abstracts of presentations at key conferences in endocrinology

ea0073aep2 | Adrenal and Cardiovascular Endocrinology | ECE2021

Characteristics of pheochromocytomas/paragangliomas in Flemish population

Sofia Maria Lider Burciulescu , Guy T’Sjoen , Badiu Corin , Bruno Lapauw

IntroductionPheochromocytomas (PHEO) and paragangliomas (PGL) are rare neuroendocrine tumors of the autonomic nervous system, originating from neural crest. Despite the same embryological origin, there are some differences between them.AimWe searched for differences in method of discovery, clinical and biochemical phenotype, of sporadic vs hereditary PHEO/PGL in a cohort of Flemish patients.<p class="abst...

ea0073aep586 | Reproductive and Developmental Endocrinology | ECE2021

Changes in androgen profile in transgender women with or without gonadectomy

Collet Sarah , Defreyne Justine , Kiyar Meltem , De Meijer Delphine , Nobels Sarah , den Heijer Martin , Guy T’Sjoen

ObjectivesThe European Network for Investigation of Gender Incongruence (ENIGI) is a multicenter prospective cohort study. All participants receive a standardized gender affirming treatment (GAHT) protocol including regular follow-up. The current study compared changes in androgens upon starting GAHT and during follow-up in transgender women (TW) with or without gonadectomy by investigating serum total testosterone (TT), calculated free testosterone (cFT...

ea0073aep451 | General Endocrinology | ECE2021

The (epi)genetic basis of gender incongruence

Fernandez Rosa , Collet Sarah , Ramirez Karla , Kiyar Meltem , Delgado-Zayas Enrique , Guy T’sjoen , Guillamon Antonio , Mueller Sven C , Eduardo Pásaro

In mammals, the gonads and the brain develop from bipotential organs that will differentiate into female or male organs, during a critical period of development. This process begins with the production of testosterone by the testes, which will be converted into estradiol in the brain, by the aromatase. While the end is defined by the moment when the inhibition of androgens (in males), or treatment with estrogens (in females), stops having an effect on brain dimorphism. But in ...