ea0029p1360 | Pituitary Basic | ICEECE2012
Moscardini F.
, Domingos M.
, Haddad N.
, Cabral L.
, Miranda-Alves L.
, Nasciutti L.
Cushing Disease (CD) is a serious endocrine disorder that is primarily caused by an ACTH-secreting pituitary adenoma. Current treatments of CD present low efficiency in controlling the tumor mass growth and reducing the release of ACTH. This work investigates a possible new therapy for the treatment of pituitary tumors. Using a nanoparticle extract (nanoOse) of a typical Brazilian palm tree, we verify the in vitro effects of this extract on a ACTH-secreting mouse pituit...