Searchable abstracts of presentations at key conferences in endocrinology

ea0063p1031 | Interdisciplinary Endocrinology 2 | ECE2019

Acid sphingomyelinase deficiency unusually associated with severe delay of growth

Naifar Manel , Kallel Faten , HadjKacem Faten , Messoud Olfa , Messedi Sondes , Abid Mohamed , Ayedi Fatma

Background: Acid Sphingomyelinase Deficiency (ASMD) is a rare lysosomal storage disease caused by mutations in the SMPD1 gene. Typically, the p.Arg610del homozygotes had normal linear growth.Case report: We reported the cases of 2 Tunisian brothers aged 23 and 13 years respectively, who have been admitted for splenomegaly and polyadenopathies. Physical examination showed pubertal and growth delay for both cases. Biological evaluation showed mode...

ea0049ep667 | Obesity | ECE2017

Obesity and infertility among Tunisian women of reproductive age: about 40 cases

Hadjkacem Faten , Rebai Mariem , Saidane Dalila , Ghorbel Dorra , Abid Mohamed

Obesity is on the increase worldwide and mainly in women of reproductive age. In turn, it is associated with various reproductive complications. To assess the detrimental effect of obesity on reproductive health and the means of its management, this retrospective cohort study of 40 obese and infertile women has been conducted in the department of endocrinology and diabetology of Hedi Chaker hospital in Sfax-Tunisia from 2009 to 2014. These patients have a mean age of 34 years ...

ea0056p343 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Nutrition of non-fasting patients with diabetes during the month of Ramadan

Lassoued Najoua , Abid Neila , HadjKacem Faten , Charfi Nadia , Abid Mohamed

Introduction: Fasting during the month of Ramadan is the most observed religious practice by Muslims. Diabetes is one of the condition that exempt Muslims from fasting because of the risk of complications. The International Diabetes Federation states that high-risk patients ‘should not fast’. The objective of this study was therefore to evaluate the daily food intake during the month of Ramadan in non-fasting patients with diabetes in order to detect diet mistakes ma...

ea0090ep1069 | Thyroid | ECE2023

Thyroid pathology and hypofertility

Ben Salah Raida , Hadjkacem Faten , Somauroo Seddiqa , Abid Mohamed , Bahloul Zouhir

Introduction: Thyroid pathology is common in women of reproductive age. Evaluation of thyroid function is classically recommended in cases of recurrent abortion. The presence of dysthyroidism or antithyroid antibodies increases the risk of abortion. We report two observations of hypofertility related to thyroid pathology and discuss the therapeutic course.Case 1: A 33 year old woman was referred for etiological investigation of recurrent abortion. She pr...

ea0063gp29 | Diabetes and Cardiovascular Disease | ECE2019

Systematic screening of masked hypertension in normotensive type 2 diabetic patients

Ghorbel Dorra , Hadjkacem Faten , Triki Faten , Mnif Mouna , Charfi Nadia , Rekik Nabila , Kammoun Samir , Abid Mohamed

Introduction: Masked hypertension (MH) is a relatively recent description leading to a similar cardiovascular risk as permanent hypertension. Masked hypertension is more common among diabetic patients.Methods: This was a case-control study. We performed 24-hour ambulatory BP in 53 type 2 diabetic patients normotensive in clinical measurement. We compared both Masked Hypertension and Normotensive groups according to clinical/laboratory parameters and targ...

ea0063p1058 | Pituitary and Neuroendocrinology 3 | ECE2019

Pituitary apoplexy: diagnosis, management and outcome in 44 patients

Gargouri Imen , Hadjkacem Faten , Mnif Mouna , Walha Mohamed , Rekik Nabila , Charfi Nadia , Ayadi Fatma , Abid Mohamed

Introduction: Pituitary apoplexy (PA) is a rare incident defined by the occurrence of necrosis and/or haemorrhage of the pituitary gland. PA is a clinical syndrome characterized by the sudden onset of headache, vomiting, visual impairment and decreased consciousness in some cases. The objectives of our study are to describe its clinical, biological and imaging features as well as the management of PA in the region of Sfax.Patients and methods: It is a re...

ea0063ep102 | Pituitary and Neuroendocrinology | ECE2019

Thyrotropin-producing pituitary adenoma: 3 case reports

Hadjkacem Faten , Gargouri Imen , Bensalah Dhouha , Neifar Manel , Boujelben Khouloud , Charfi Nadia , Rekik Nabila , Abid Mohamed

Introduction: Thyrotropin-secreting pituitary adenomas represent less than 1% of all pituitary adenomas. Usually, patients present mild or moderate signs of hyperthyroidism and Hormonal evaluation shows increased free thyroid hormone concentration with detectable, normal or increased serum thyrotropin (TSH) level. Herein we report three cases of thyrotropin adenomas with particular clinical and biological features.Observations: Three patients, aged 25 38...

ea0070aep688 | Pituitary and Neuroendocrinology | ECE2020

Do cardiovascular risk factors predispose to pituitary apoplexy?

Gargouri Imen , Faten Hadjkacem , Othman Wafa Ben , Mouna Mnif , Mohamed Abid

Introduction: Pituitary apoplexy (PA) is a rare incident defined by the occurrence of necrosis and/or haemorrhage of the pituitary gland. The low incidence of PA makes it difficult to bring out from the studies its precipitating factors and especially its relationship with cardiovascular risk factors (CVR). The objectives of this studies were to characterize a number of patients with PA and to establish the link between PA and their CVRs.Methods: It is a...

ea0056p103 | Clinical case reports - Pituitary/Adrenal | ECE2018

Paraganglioma of the prostate: a case report

Kalthoum Mehdi , Hadjkacem Faten , Elleuch Mouna , Ghorbel Dorra , Charfi Nadia , Naifer Manel , Abid Mohamed

Introduction: Extra-adrenal paragangliomas are neoplasms arising from cells of neural crest origin anywhere along the distribution of the sympathoadrenal neuroendocrine system. Nearly 85% are intra-abdominal, 12% are intrathoracic, and 3% are cervical. 1 Some of the unusual sites for paragangliomas include the kidney, urethra, urinary bladder, prostate.Case report: A 27-year old man presented with sever hypertensive crisis. He had a medical history of hi...

ea0056p144 | Female Reproduction | ECE2018

Female fertility in congenital adrenal hyperplasia

Gargouri Imen , Mnif Fatma , Ajili Rihab , Hadjkacem Faten , Sessi Salwa , Kammoun Mahdi , Mnif Mouna , Abid Mohamed

Introduction: Congenital adrenal hyperplasia (CAH) is a genetic disease with autosomal recessive inheritance. The deficit in 21-hydroxylase (21-OH) is by far the most common enzyme deficiency CAH, since it represents 95% of the cases. Fertility in wome is found to be reduced due to hormonal, mechanical and psychological factors.Patients and methods: It is about a descriptive and prospective study conducted in 15 patients collected in the endocrinology de...