Endocrine Abstracts

Introduction: Prolactin-secreting tumors or prolactinomas comprise the most common pituitary tumor type, acconting of 47-66% of all pituitary tumors. These tumors can be treated with dopaminergic drugs (DA) however 10-15% of prolactinomas are DA resistant.Case 1: A 39 years old man followed for a geant agressif prolactinoma discovered following a progressive decline in visual acuity and associated with visual impairment (diplopia), the MRI of the sellar ...

Introduction: Pituitary adenomas, more recently referred to as pituitary neuroendocrine tumors (PitNets) from other organs, are common neoplasms comprising 10 to 20% on intracranial tumors. Null cell adenoma is a diagnosis of exclusion that requires immunonegativity for all adenohypophyseal hormones and a lack of cell type-specific transcription factors. It represents 0,6% of all pituitary tumors. Case: A 55 years old women with a history of treated thyr...

Introduction: Pituitary abscess (PA) is a rare accounting for 0,2-1% of all sellar lesions, it is generally classified as primary or secondary according to their etiopathogenesis. Case: A 20-year-old female with a history of vulvitis a year ago, dental abscesses on multiple dental caries who presented 05 months ago with intracranial hypertension syndrome in a febrile context. One-month later amenorrhea sets in as well as polyuropolydeptic syndrome, hormo...

Introduction: Pituitary adenoma and meningioma are the most benign tumors in the central nervous system (meningioma 35,9%, pituitary tumor: 15,5%). Pituitary adenoma associated with meningioma without a history of radiotherapy is extremely rare.Case: A 70 years old man operated for post-traumatic subdural hematoma in whom the brain MRI (magnetic resonance imaging) had also shown a macroadenoma, completed with an MRI of the sellar region which were confir...

Introduction: High-grade astrocytoma with piloid features (HGAP) is arecently described brain tumor entity defined by a specific DNA methylation profile. HGAP has been integrated in the World Health Organization classification of central nervous system tumors 2021.Clinical presentationA 53-year -old woman was admitted to our department with chief complaints of headache with rapid deterioration in visual acuity over a period of 6 months. During the course of the disease, the pa...

Background: Hypophysitis is a rare pathology its symptoms and radiological signs are non-specificy making its diagnosis difficultCase Description: A 62-year-old Women, mother of 5 children, with a History of type 2 diabetes mellitus, hypothyroidism. During a period of fasting, the patient presented with profound asthenia, a tendency to hypotension. A severe hyponatremia at 119 mmol/l was diagnosed. The patient received urgent treatment. The hormonal biol...

Background: Pituitary apoplexy (PA) is a rare neuroendocrine emergency due to acute ischemic infarction or hemorrhage of the pituitary gland. We report a case of apoplexy manifesting with isolated ophtalmoplégia.Case description: We report the case of a 48-year-old man with a history of hypertension, type 2 diabetes mellitus, and dyslipidemia. Consult a private ophthalmologist following the sudden appearance of double vision and sagging of the right...