Searchable abstracts of presentations at key conferences in endocrinology

ea0063p719 | Pituitary and Neuroendocrinology 2 | ECE2019

Control of hyperglycemia in a young male patient with gigantism during transition: a case report

Berta Eszter , Lengyel Inez Mercedesz , Halmi Sandor , Puskas Istvan , Felszeghy Enikő , Balogh Zoltan , Nagy Endre V , Bodor Miklos

Introduction: In acromegaly GH excess leads to impaired insulin sensitivity with an alteration of beta-cell function. The consequent hyperglycemia leads to a further increased cardiovascular risk and mortality.Case report: A 16 years old patient was first referred to the Department of Pediatrics in 2014 with accentuated growth since the age of 10. The reason of the first referral was a sport injury (head trauma during playing basketball). Sella MRI depic...

ea0037gp.27.08 | Thyroid – hyperthyroidism and treatment | ECE2015

There is a detectable immune activity in the orbits of all patients diagnosed with Graves' disease regardless of later development of Graves' orbitopathy

Berta Eszter , Ujhelyi Bernadett , Szabados Lajos , Galuska Laszlo , Erdei Annamaria , Gazdag Annamaria , Halmi Sandor , Nagy Endre , Bodor Miklos

Graves’ orbitopathy (GO) is a common complication of Graves’ disease (GD) which is often responding poorly to therapy. GO may develop before or together with, or during the course of GD. In an individual patient, the development of GO cannot be predicted. We assumed that orbital autoimmune activity is predictable using orbital 99mTc-labelled diethylenetriamine pentaacetic acid (99mTc-DTPA) SPECT. We aimed to determine whether any orbital autoimmune activity can be id...

ea0056p1095 | Thyroid (non-cancer) | ECE2018

Serum chemerin and other dyslipidemia markers in patients with autoimmune thyroiditis

Berta Eszter , Harangi Mariann , Varga Viktoria E , Lorincz Hajnalka , Seres Ildiko , Halmi Sandor , Nagy Endre V , Paragh Gyorgy , Bodor Miklos

Aim: Chemerin, a recently discovered adipokine produced by the adipose tissue and liver, along with other atherosclerosis markers, was associated lately with metabolic syndrome and acts as chemoattractant for immune cells may also regulate immune cell properties. Autoimmune Hashimoto’s thyroiditis even with sTSH levels corrected to be within the normal range values may be accompanied by dyslipidemia presenting increased total-C, TG, LDL-C, and Lp(a), all of which are pote...

ea0081ep400 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Association of chemerin and serum advanced glycation end products in patients with autoimmune thyroiditis

Bak-Csiha Sara , Halmi Sandor , Hutkai David , Molnar Istvan , Katko Monika , Lőrincz Hajnalka , Harangi Mariann , Paragh Gyorgy , Nagy Endre , Bodor Miklos , Eszter Berta

Background: Hypothyroidism due to autoimmune thyroiditis leads to atherogenic lipid profile and metabolic changes. The formation of advanced glycation end products (AGEs) increases with hyperglycemia, hyperlipidemia and oxidative stress. Degradation of AGEs after AGEs-receptor 1-mediated intracellular uptake and renal clearance of soluble AGEs generated by certain cells like macrophages play a crucial role in the decrement of circulating AGEs level. Chemerin is an adipokine pr...

ea0092ps2-11-03 | Miscellaneous 2 | ETA2023

Evaluation of advanced end glycation products (AGES), their solube receptors (SRAGE) and the components of oxidative stress in patients with hashimoto’s thyroiditis on levothyroxine substitution

Csiha Sara , Molnar Istvan , Halmi Sandor , Hutkai David , Lorincz Hajnalka , Somodi Sandor , Katko Monika , Harangi Mariann , Paragh Gyorgy , Nagy Endre V. , Bodor Miklos , Berta Eszter

Background: Advanced glycation end products (AGEs) are heterogenous group of irreversible chemical moieties originated from non-enzymatic glycation and oxidation of proteins, nucleic acids, and lipids. The engagement of AGEs with their chief cellular receptor (RAGE) activates signaling pathways contributing to the progression of chronic diseases like autoimmune thyroiditis, type 2 diabetes mellitus and its complications. Soluble RAGE (sRAGE) prevents AGE-RAGE interaction in a ...