Searchable abstracts of presentations at key conferences in endocrinology

ea0059p026 | Adrenal and steroids | SFEBES2018

Evaluation of glucocorticoid secretion in an adrenal incidentaloma cohort

Mason Oliver , Hanna Fahmy , Keevil Brian , Ensah Grace , Issa Basil

Background: Adrenal incidentalomas (AI) are being seen frequently in endocrine clinics due to increased cross-sectional imaging with a prevalence of 4% (7% in patients >70 years) of abdominal CT scans. The majority of these tumours are benign and non-functional, but identifying malignancy and functionality is important. Excess cortisol production is the commonest endocrinopathy associated with AI, with a reported prevalence of ~10%. The overnight 1 mg dexamethasone suppres...

ea0021p244 | Pituitary | SFEBES2009

Management of non-functioning pituitary adenomas in a University Hospital: aretrospective analytical audit

Varadhan Lakshminarayanan , Mukherjee Arjun , Brown Maureen , Clayton Richard , Hanna Fahmy

Introduction: Pituitary tumors account for 15% of all intracranial neoplasms and could remain asymptomatic for a significant period. We conducted a retrospective analysis to assess pattern of referrals and management of non-functioning pituitary adenomas at our tertiary referral centre.Methods: Data was collected on referrals for NFA received at our university hospital from 2005 to 2008. Medical records, radiology reports and endocrine department data we...

ea0086p75 | Metabolism, Obesity and Diabetes | SFEBES2022

Health Inequality and its link to HbA1c Test Recovery in a Developed Health Economy: In a ‘Nearly Post COVID-19’ World

Heald Adrian , Holland David , Duff Christopher J , Scargill Jonathan , Hanna Fahmy , Fryer Anthony

Background: We previously showed that in first 6 months of the UK Covid-19(C19) pandemic >6.6million HbA1c tests were missed, including 1.4million in people with diabetes(DM). Furthermore, C19 more significantly impacts people with DM / socioeconomically disadvantaged individuals.Aim: To examine variability in recovery rate of HbA1c testing, and links to demographics, including deprivation status.Methods: We examined HbA1c test...

ea0070oc1.5 | Adrenal and Cardiovascular Endocrinology | ECE2020

The utility of salivary cortisol and cortisone measurement in the assessment of cortisol secretion in adrenal incidentalomas

Issa Basil , Keevil Brian , Graham Neethu , Ensah Grace , Belcher John , Fryer Anthony , Hanna Fahmy

Backgound: Adrenal incidentalomas (AI) are lesions that are incidentally identified while scanning for other conditions. The European Society of Endocrinology guidelines recommend that all patients with AI should undergo an overnight dexamethasone suppression test (ONDST) for the evaluation of autonomous cortisol secretion as defined by failure of suppression of cortisol to < 50 nmol/l. The reported prevalence of this is high (50% of patients in a recent publication) and m...

ea0013p293 | Thyroid | SFEBES2007

Persistent hypothyroidism despite optimal therapy: time to rethink

Varughese George , Tahrani Abd , Khan Tahir , Davis Julie , Clayton Richard , Hanna Fahmy

We report a 47-year old lady who was initially diagnosed to have primary hypothyroidism nearly four years ago; on treatment with levothyroxine sodium (LT4) 150 μcg daily. Despite reasonable doses of LT4, and being fully compliant with her therapy, at no stage her TSH was less than 20 mU/L (Table-1). Malabsorption was ruled out and there were no clinical features to suggest this. When she was reviewed...

ea0077p64 | Metabolism, Obesity and Diabetes | SFEBES2021

The Variability In Glycosylated Haemoglobin (HbA1c) Testing Interval In People With Diabetes Is Linked To Long-Term Diabetes Control, Independent of HbA1c Test Interval

Heald Adrian , Holland David , Stedman Michael , Duff Chirstopher J , Green Lewis , Scargill Jonathan , Hanna Fahmy WF , Wu Pensee , Fryer Anthony A

Introduction: Worldwide guidance advocates regular HbA1c testing for people with diabetes mellitus, usually 2-4/yr. We previously showed that HbA1c testing frequency is linked to outcome in terms of HbA1c control. Here we examine the effect of variability (standard deviation = SD) in test interval on change in HbA1c over 7 yrs (Jun 2012-Jul 2019) using laboratory data.Methods: We focused on people with HbA1c within the first 2 years who also had a HbA1c ...