Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep96 | Adrenal and Cardiovascular Endocrinology | ECE2020

Confirmatory testing of primary aldosteronism with saline infusion test and LC-MS/MS

Teresa Fuss Carmina , Brohm Katharina , Kurlbaum Max , Hannemann Anke , Kendl Sabine , Fassnacht Martin , Deutschbein Timo , Hahner Stefanie , Kroiss Matthias

Objective: The saline infusion test (SIT) is a standard confirmatory test for primary aldosteronism (PA) and based on impaired aldosterone suppression in PA compared to essential hypertension (EH). In the past, aldosterone was quantified using immunoassays (IA). Due to the more widespread use of liquid chromatography tandem mass spectrometry (LC-MS/MS) in clinical routine, we aimed at a method-specific aldosterone threshold for the diagnosis of PA during SIT and explored the d...

ea0070aep151 | Bone and Calcium | ECE2020

Cardiovascular status in chronic hypoparathyroidism – a single-center analysis in 133 patients compared to the general german population

Teresa Fuss Carmina , Gronemeyer Karen , Hermes Franca , Dörr Marcus , Koschker Ann-Cathrin , Nordbeck Peter , Hannemann Anke , Hahner Stefanie

Introduction: Even though it is well known that long-term complications, such as renal insufficiency and brain calcifications can occur in patients with hypoparathyroidism (HPT), the risk of cardiovascular diseases still remains unclear.Objective: To perform a systematic assessment of cardiovascular function in a well-characterized cohort of patients with HPT compared to population-based controls.Methods: 133 patients with chronic ...

ea0037ep77 | Adrenal cortex | ECE2015

Prevalence of neoplasms in patients with primary aldosteronism

Lang Katharina , Weber Katrin , Quinkler Marcus , Dietz Anna , Wallaschofski Henri , Hannemann Anke , Vonend Oliver , Willenberg Holger , Reincke Martin , Allolio Bruno , Hahner Stefanie

Context: Primary aldosteronism (PA) is the most common cause of secondary hypertension. Aldosterone excess can cause oxidative stress and respectively DNA damage in vitro and in vivo and increased levels of oxidative stress have been demonstrated in PA patients. Single case reports describe a coincidence of PA with renal cell carcinoma (RCC) and other tumours. However, so far no data on the prevalence of benign and malignant neoplasms in patients with PA exis...