Searchable abstracts of presentations at key conferences in endocrinology

ea0077oc5.2 | Bone and Calcium | SFEBES2021

Gastric inhibitory polypeptide (GIP) reduces human osteoclast activity by suppressing multiple signalling pathways

Hansen Morten S , Soe Kent , Gorvin Caroline M , Frost Morten

Gastric inhibitory polypeptide (GIP) is a post-prandially secreted gut hormone that acts upon the GIP-receptor (GIPR), to stimulate insulin secretion. Animal studies indicate that GIP influences bone remodelling, and in humans, GIP administration decreases levels of bone resorption markers. However, the mechanisms by which GIP influences resorption remain to be elucidated. Therefore, we investigated how GIP (10nM) affects bone cell activity using primary human osteoclasts, hum...

ea0032oc3.6 | Thyroid | ECE2013

Subclinical hyperthyroidism and risk of cardiovascular and all-cause mortality

Selmer Christian , Olesen Jonas , Madsen Jesper , Faber Jens , Hansen Peter , Pedersen Ole , Hansen Morten , Torp-Pedersen Christian , Gislason Gunnar

ESE Young Investigator AwardBackground: It is still discussed if subclinical hyperthyroidism and ‘high-normal’ thyroid function are risk-factors for cardiovascular mortality.Objectives: To examine the risk of cardiovascular and all-cause mortality in relation to subclinical hyperthyroidism.Methods: Patients consulting their general practitioner from 2000 to 2009 in Copenhagen, Denmark, who ...